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    Preclinical

    New radiopharmaceutical shows therapeutic efficacy in preclinical model of ovarian disease

    Preclinical trials of a new radiopharmaceutical to treat ovarian cancer have produced effective results, dramatically restricting tumor growth and diminishing tumor mass. Designed especially for ovarian cancers that are resistant to conventional therapies, the new radiopharmaceutical could be produced in 25 minutes at reduced cost, which contributes to better efficiency compared with alternative procedures. This

    Small molecule drug can weaken the triggers of neuroinflammation, preclinical review shows

    Neuroinflammation may cause worse outcomes in cases of stroke, injuries to the brain or injury, and can increase the severity of neurodegenerative diseases such as ALS, Parkinson’s, or Alzheimer’s. This suggests that reducing neuroinflammation might be an exciting new method to treat neurological disorders and neuropathic pain caused by neuroinflammation. In a preclinical study ,

    Novel antibody candidate shows powerful binding to different SARS-CoV-2 variant mutations

    Twist Bioscience Corporation today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19. The Coronavirus Immunotherapy Consortium (CoVIC) is an academic-industry-non-profit