Microorganisms utilize vile methodology to vanquish antibody that battle cystic fibrosis Kumar Jeetendra | February 28, 2021 University of Montana researchers and their partners have found a slimy strategy used by bacteria to conquer antibiotics and other medications used to combat infections afflicting individuals with cystic fibrosis. Cystic fibrosis is a life-threatening illness which causes persistent lung infections and limits an individual’s ability to breathe over time. A frequent strain of bacteria, …
Genomic surveillance can help recognize how SARS-CoV-2 spreads in care homes Kumar Jeetendra | March 4, 2021 Care homes are at high risk of experiencing outbreaks of COVID-19, the disease brought on by SARS-CoV-2. Older people and people affected by heart disease, respiratory disease and type 2 diabetes – all of which increase with age – are at greatest risk of severe disease and even death, which makes the care home population …
FDA issues emergency use approval for T-Detect COVID Test Kumar Jeetendra | March 7, 2021 Now, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for its T-Detect COVID Exam developed by Adaptive Biotechnologies. The T-Detect COVID Evaluation is a next generation sequencing established (NGS) test to assist in identifying people with an adaptive T cell immune response to SARS-CoV-2, indicating recent or prior infection with SARS-CoV-2. …
Compounds in green and black tea relax blood vessels by activating ion channel proteins Kumar Jeetendra | March 9, 2021 A new study from the University of California, Irvine shows that chemicals in both black and green tea relax blood vessels by activating ion channel proteins in the blood vessel wall. The discovery helps explain the antihypertensive properties of tea and could lead to the design of new blood pressure-lowering medications. Released in Cellular Physiology …
Deforestation in the Amazon builds variety of antibiotic-resistant bacteria Kumar Jeetendra | March 12, 2021 In Brazil, a study conducted by researchers affiliated with the University of São Paulo (USP) and collaborators showed that deforestation in the Amazon causes an increase in the diversity of antibiotic-resistant bacteria. An article on the study, published in Soil Biology and Biochemistry, compares the microorganisms that live in the land of indigenous forest with …
Study offers understanding into metabolic pathways hijacked by SARS-CoV-2 for viral replication Kumar Jeetendra | March 16, 2021 When SARS-CoV-2, the virus which causes COVID-19, infects a human cell, it quickly begins to replicate by seizing the cell’s existing metabolic machinery. The infected cells churn out thousands of viral genomes and proteins while halting the creation of their own sources. Researchers from Brigham and Women’s Hospital, Massachusetts General Hospital (MGH), and the Broad …
CN Bio presents the PhysioMimix™ OOC Multi-Organ Microphysiological System Kumar Jeetendra | March 17, 2021 CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS. The next-generation system unites CN Bio’s in vitro 3D liver model, whose phenotype and functions mimic that in vivo, with a range of other organs to …
INTEGRA’s electronic pipettes empower reproducible examination in microbial analysis Kumar Jeetendra | March 17, 2021 Bacterial evolution studies involve analysis of large sample numbers, requiring compact, reproducible pipetting processes to effectively characterize the qualities of different strains. Dr Astrid Altamirano-Junqueira, who completed her doctoral studies into the growth of bacterial motility in the School of Biological Studies at Reading University, discussed how these digital pipettes aided her research:”My focus was …
Intense openness of lung tissue to vape airborne lesserly affects gene expressionthan cigarette smoke Kumar Jeetendra | March 21, 2021 A new peer-reviewed study published in the journal Toxicological Research & Application reveals acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression in contrast to smoke from combustible cigarettes. The study included sub-cytotoxic vulnerability to cells in a 3D human bronchial model (MucilAirTM) to nicotine-containing vape …
Bacteria residing within inside tumor cells can support malignant growth immunotherapy Kumar Jeetendra | March 22, 2021 Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. The study may also help clarify the connection between immunotherapy and the intestine microbiome, describing the findings of earlier research that the microbiome impacts the success of immunotherapy. Immunotherapy remedies of the last decade or so have dramatically improved healing …
Presenting Inhalytix™: Solution for analysing and managing inhaler test data from Copley Kumar Jeetendra | March 22, 2021 Inhalytix™ is a completely new software solution from Copley, the global leader in inhaler testing equipment, that brings a standardized approach to cascade impactor data analysis, efficiently converting raw data into performance-defining metrics for all inhaled products. Cascade impactors determine aerodynamic particle size distribution (APSD), a critical quality attribute for inhaled drug delivery. Inhalytix™ is …
Small SARS-CoV-2 protein may have huge ramifications for future COVID-19 medicines Kumar Jeetendra | April 12, 2021 A very small protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future therapies, according to a team of Penn State researchers. Using a novel toolkit of approaches, the scientists uncovered the first full structure of the Nucleocapsid (N) protein and discovered how antibodies from COVID-19 patients interact with …
