Study shows tofacitinib medication can fix porousness absconds in the digestive tract Kumar Jeetendra | October 6, 2020 A team of researchers led by biomedical scientist Declan F. McCole in the University of California, Riverside, has found that the medication tofacitinib, also called Xeljanz and approved by the FDA to treat rheumatoid arthritis and ulcerative colitis, can fix permeability defects in the intestine. Study results appear in the Journal of Crohn’s and Colitis. …
Study gives conceivable clarification to reformist course of different sclerosis in mice Kumar Jeetendra | October 17, 2020 People with multiple sclerosis (MS) gradually develop increasing functional impairment. Researchers at Karolinska Institutet in Sweden have found a possible explanation for the progressive course of this disease in mice and how it can be reversed. The analysis, which is published in Science Immunology, can prove beneficial to future treatments. MS is a chronic inflammatory …
CBD could lessen lung harm brought about by COVID-19 Kumar Jeetendra | October 19, 2020 One way CBD appears to reduce the”cytokine storm” that damages the lungs and kills many individuals with COVID-19 is by enabling an increase in levels of a natural peptide called apelin, which is proven to reduce inflammation and whose levels are dramatically reduced in the face of this storm. Dental College of Georgia and Medical …
Coating implant material with artificial bone unresolved issue irritation Kumar Jeetendra | October 23, 2020 The history of implants can be traced back all of the way to A.D. 1 when wrought iron dental implants were used in Ancient Rome. Despite the long term, however, there are still lots of problems associated with implant processes like a loose implant resulting from slow integration into the bone tissue or an inflammation …
Myeloid cells can smother insusceptible reaction, advance cerebrum metastasis Kumar Jeetendra | October 28, 2020 Scientists have long thought that the brain protects itself from an aggressive immune response to keep inflammation down. However, that evolutionary management may work against it when a cancer cell tries to spread to the brain, researchers at the University of Notre Dame have found. In recently published research in the journal Cell, researchers showed …
Microorganisms in the lungs could impact lung cancer progression and prognosis Kumar Jeetendra | November 11, 2020 Bottom Line: Enrichment of the lungs with oral commensal microbes has been correlated with advanced stage disease, worse prognosis, and tumor progression in patients with lung cancer. Journal in Which the research was Published: Cancer Discovery, a journal of the American Association for Cancer Research Author: Leopoldo Segal, MD, director of the Lung Microbiome Program, …
Dexamethasone use could reduce immune checkpoint inhibitor viability in glioblastoma patients Kumar Jeetendra | November 25, 2020 Bottom Line: One of patients with glioblastoma getting an immune checkpoint inhibitor, people who obtained the corticosteroid dexamethasone at baseline for cerebral edema had significantly worse overall survival. Journal Where the Study was Released: Clinical Cancer Research, a journal of the American Association for Cancer Research Author: David A. Reardon, MD, clinical director of the …
Researchers distinguish systems behind inflammasome initiation by fungal pathogens Kumar Jeetendra | December 3, 2020 Researchers at St. Jude Children’s Research Hospital have identified the mechanisms behind inflammasome activation driven by infection with the fungal pathogen Aspergillus fumigatus. Fungal infection, especially with A. fumigatus, is a leading cause of infection-associated deaths in people with compromised immune systems. The work provides clues to a potential therapeutic approach for treating infectious and …
Study affirms most basic complexities related with COVID-19 Kumar Jeetendra | December 8, 2020 A large study of patients in america who contracted coronavirus disease 2019 (COVID-19) confirms many complications of the disease, according to new research in CMAJ (Canadian Medical Association Journal). Understanding the full range of associated conditions can aid in prognosis, guide treatment decisions and better inform patients as to their actual risks for the variety …
Colon lining discharges hydrogen peroxide to shield the body from gut microorganisms Kumar Jeetendra | December 10, 2020 Scientists at UC Davis Health have discovered that an enzyme in the colon lining releases hydrogen peroxide (H2O2) – a known disinfecting chemical – to protect the body from gut microbes. Their study, published Dec. 9 in the journal Cell Host and Microbe, sheds light on the way microorganisms are spatially organized in the colon. …
Smoking traditional cigarettes alongside e-cigarettes causes harmful wellbeing impacts Kumar Jeetendra | January 4, 2021 Smoking traditional cigarettes in addition to using e-cigarettes leads to harmful health effects like smoking cigarettes exclusively, according to new research published today in the American Heart Association’s flagship journal Circulation. Smoking, a well-known link to cardiovascular disease and death, seems to be on the decline. While using e-cigarettes, known as vaping, is increasingly popular, …
Boosting a characteristic cell cycle could bring down ventilator-related lung damage Kumar Jeetendra | January 12, 2021 An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is very likely to cause further lung damage. In a new study, scientists identified a molecule that’s produced by immune cells during mechanical ventilation to try to decrease …