Analysts recognize interface among ALS and collection of DNA-RNA hybrids in the genome Kumar Jeetendra | January 13, 2021 Researchers from the University of Seville and the University of Pavia have identified a connection between Amyotrophic Lateral Sclerosis (ALS) and the accumulation of DNA-RNA hybrids in the genome. The accumulation of these hybrids causes increased genomic damage and boosts genetic instability. This finding will make it possible to better understand the molecular basis of …
The Cancer Microbiome Atlas gives more clear picture of microbiota living in organs Kumar Jeetendra | January 14, 2021 Biomedical engineers at Duke University have devised an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). With a clearer picture of the microbiota living in a variety of organs in both healthy and cancerous states, researchers will now have the ability to find new biomarkers of disease and better understand …
National consortium to examine the impacts of arising SARS-CoV-2 mutations Kumar Jeetendra | January 16, 2021 The’G2P-UK’ National Virology Consortium will study how mutations in the virus affect key outcomes like how transmissible it is, the seriousness of COVID-19 it causes, and the potency of vaccines and treatments. The Consortium will bring together leading virologists from 10 research institutions. They will work together with the COVID-19 Genomics UK (COG-UK) consortium, which …
Recently recognized supplement helps the gut review earlier diseases and execute attacking bacteria Kumar Jeetendra | January 17, 2021 Scientists studying the body’s natural defenses against bacterial disease have identified a nutritional supplement –taurine–that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn). The finding, published in the journal Cell by scientists from five institutes of the National Institutes of Health, could help efforts seeking alternatives to antibiotics. …
Research finds new proof about the systems controlling skin repair and regeneration Kumar Jeetendra | January 19, 2021 As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has discovered new evidence deep within the skin about the mechanisms controlling skin renewal and repair. Skin’s barrier function gives it the unique ability to fight winter woes and keep …
Scientists find uncommon hereditary disorder that influences the brain, heart and facial highlights Kumar Jeetendra | January 21, 2021 Researchers at the National Institutes of Health have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart and facial features. Named linkage-specific-deubiquitylation-deficiency-induced embryonic defects syndrome (LINKED), it is caused by a mutated version of the OTUD5 gene, which interferes with key molecular actions in embryo development. The findings indicate …
UC research group utilizes zebrafish to contemplate a quality change that causes intrinsic scoliosis Kumar Jeetendra | January 24, 2021 Popular in aquariums throughout the world, the zebrafish is native to South Asia. But here in a Cincinnati Children’s laboratory, the freshwater variant plays a vital role in scientific discovery. The patterning of the zebrafish’s spine gives the appearance of stripes; it is controlled by segmentation genes which function as a clock. Zinani is part …
Study shows why children of obese moms have inclination to create metabolic illnesses Kumar Jeetendra | January 27, 2021 A Brazilian study published in the journal Molecular Human Reproduction helps understand why overweight mothers often have children with a propensity to develop metabolic disease during their lifetime, according to previous research. According to the authors,”transgenerational transmission of metabolic disorders” may be associated with Mfn2 deficiency in the mother’s oocytes (immature eggs). Mfn2 refers to …
Gene panel test empowers exceptionally exact diagnosis of liposarcomas Kumar Jeetendra | February 5, 2021 Scientists have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel evaluation which allows for highly accurate diagnosis of the most frequent kinds of liposarcoma. The new assay is described in The Journal of Molecular Diagnosis, published by Elsevier. Liposarcomas are a type of malignant cancer that is …
New device empowers study of SARS-CoV-2 mutant range by ultrasequencing Kumar Jeetendra | February 15, 2021 SARS-CoV-2 genome is three times larger than flu genome. Both consist of NRA molecules which mutate when replicate. It is essential to know its mutant spectrum, in other words, its”fingerprints”, to achieve an appropriate treatment that reduces its infectivity -the capacity of pathogens to invade organisms and cause infections-, since its composition of variables could …
Study discoveries help clarify the variety of cancers in various Li-Fraumeni patients Kumar Jeetendra | February 23, 2021 The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several kinds of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations. Recent studies suggest that some people with inherited p53 …
Retroviruses attacking the koala germline add to high malignant growth rates Kumar Jeetendra | February 26, 2021 Koalas are facing multiple ecological and health issues which threaten their survival. Together with habitat loss – accelerated by last year’s devastating bush fires — domestic dog attacks and road accidents, they suffer from fatal chlamydial infections and extremely high frequency of cancer. The results are reported in the journal Nature Communications. The koala retrovirus …
