Biomarkers can foresee how hereditarily identical cells act distinctively under pressure Kumar Jeetendra | January 10, 2021 A set of biomarkers not traditionally associated with cell fate can accurately forecast how genetically identical cells behave differently under pressure, according to a UT Southwestern study. The findings, published by Cell Reports as a Dec. 1 cover story, could eventually result in more predictable responses to pharmaceutical remedies. Groups of the same types of …
New investigation shows interface between intestinal microbiota and maternal behavior Kumar Jeetendra | January 30, 2021 As scientists learn more about the microorganisms that colonize the human anatomy –collectively referred to as the microbiota–one area of extreme interest is the effect that these microbes can have on the mind. A new study headed by Salk Institute scientists has identified a strain of E. coli bacteria that, when living in the guts …
Hamilton BiOS® Automated Sample Storage System Selected for New Health Sciences Research Building (HSRB)- II at Emory University Kumar Jeetendra | February 9, 2021 Hamilton Storage is very happy to confirm that the Hamilton BiOS® automatic storage system will be installed as part of a shared biorepository for preserving biological material at Emory University’s new Woodruff Health Sciences Center Health Sciences Research Building (HSRB)-II. This state-of-the-art biomedical research facility construction, including installation of the BiOS, is expected to be …
New device empowers study of SARS-CoV-2 mutant range by ultrasequencing Kumar Jeetendra | February 15, 2021 SARS-CoV-2 genome is three times larger than flu genome. Both consist of NRA molecules which mutate when replicate. It is essential to know its mutant spectrum, in other words, its”fingerprints”, to achieve an appropriate treatment that reduces its infectivity -the capacity of pathogens to invade organisms and cause infections-, since its composition of variables could …
Researchers concentrate how a single gene alteration may have isolated modern humans from extinct hominins Kumar Jeetendra | February 16, 2021 As a professor of pediatrics and molecular and cellular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders. For nearly as long, he has also been curious about the evolution of the human brain -; what …
Researchers utilize funtional test to quantify the impact of inhertited varient in BRCA2 acancer gene Kumar Jeetendra | February 21, 2021 Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variations in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS). The findings were published today in a study …
Study discoveries help clarify the variety of cancers in various Li-Fraumeni patients Kumar Jeetendra | February 23, 2021 The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several kinds of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations. Recent studies suggest that some people with inherited p53 …
Genomic Data Commons offers the biggest asset in cancer genomics Kumar Jeetendra | February 27, 2021 The National Cancer Institute’s Genomic Data Commons (GDC), launched in 2016 by then-Vice President Joseph Biden and hosted at the University of Chicago, has become one of the largest and most widely used resources in cancer genomics, with over 3.3 petabytes of data from more than 65 jobs and more than 84,000 anonymized patient cases, …
Secret genetic defects can prompt a wide range of serious illnesses Kumar Jeetendra | March 20, 2021 For the first time researchers from Hebrew University of Jerusalem, Radboudumc, Maastricht UMC+ and worldwide colleagues have gained insight to the”hidden genetic defects” of the general European population. This is important as these defects, if inherited from the father and mother, can result in all kinds of disorders in their children. Research in the Dutch …
Bacteria residing within inside tumor cells can support malignant growth immunotherapy Kumar Jeetendra | March 22, 2021 Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. The study may also help clarify the connection between immunotherapy and the intestine microbiome, describing the findings of earlier research that the microbiome impacts the success of immunotherapy. Immunotherapy remedies of the last decade or so have dramatically improved healing …
Researcher find a gene mutation connected to schizophrenia Kumar Jeetendra | March 24, 2021 Researchers at The Feinstein Institutes for Medical Research, in collaboration with Columbia University, have identified a gene mutation that could result in schizophrenia, a chronic brain disease that affects nearly 1 percent of the planet’s inhabitants. The findings, published in today in Neuron, could lead to novel treatment strategies. The research group, headed by Todd …
Scientists use genetics to recognize likely drugs for early administration of COVID-19 Kumar Jeetendra | April 12, 2021 A new study using human genetics indicates researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages. The findings appeared online in the journal Nature Medicine at March 2021. The purpose is to identify present drugs, either FDA-approved or in clinical development for other conditions, that can …