Study distinguishes protein as likely restorative objective for leishmaniasis vaccine Kumar Jeetendra | December 12, 2020 According to the results of research led by the Complutense University of Madrid (UCM), among the various strategies deployed by the Leishmania parasite to avoid tripping the human immune system is to trigger the SHP-1 protein. The parasite does this by secreting a molecule capable of interacting with the Mincle receptor expressed by antigen-presenting dendritic …
Researchers grow new serological assay for discovery of SARS-CoV-2 antibodies Kumar Jeetendra | December 13, 2020 Researchers at UC Santa Cruz have developed a novel serological assay for the detection of antibodies to SARS-CoV-2, the coronavirus which causes COVID-19. Rebecca DuBois, associate professor of biomolecular engineering at UC Santa Cruz, said the new method her staff developed is as accurate as the most dependable antibody tests now available, but is less …
Vitamin D insufficiency could clarify why autism spectrum disorder is more normal in boys Kumar Jeetendra | December 13, 2020 A deficiency in Vitamin D on the mother’s side could explain why Autism spectrum disorder is three times more common in boys, say researchers from The University of Queensland. In their latest study, Professor Darryl Eyles and Dr Asad Ali from UQ’s Queensland Brain Institute found vitamin D deficiency during pregnancy caused an increase in …
Active enzymes are expected to open full advantages of Vitamin A in carrots Kumar Jeetendra | December 14, 2020 Carrots are a good source of beta-carotene, which is a precursor of vitamin A. But to get the full health benefits of this superfood, you want an active enzyme to produce this vitamin. Studies with mice and humans reveal the conversion of beta-carotene to vitamin A reduces”bad” cholesterol in the blood. Therefore, beta-carotene can help …
First enzyme driven biocatalytic creation of nucleic acid structure blocks Kumar Jeetendra | December 15, 2020 Researchers in TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of lipoic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics. Because of this COVID 19 pandemic and the related intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is undergoing an enormous increase in …
FDA-endorsed COVID-19 medication should be utilized warily, says UC researcher Kumar Jeetendra | January 4, 2021 While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics continue to be necessary to treat hepatitis patients. One of these treatments, remdesivir, is the first and only antiviral agent of its type the U.S. Food and Drug Administration (FDA) has approved so far for COVID-19. Research at the University …
Bacteria responsible for seafood related stomach disturbs can go torpid and “wake up” Kumar Jeetendra | January 20, 2021 Vibrio parahaemolyticus is a marine bacterium that can lead to gastroenteritis in humans when eaten in raw or undercooked shellfish such as oysters and mussels. Some of these bacteria have the ability to turn dormant in poor growth conditions such as cold temperatures – and can stay in that state of hibernation for long periods …
Scientists find uncommon hereditary disorder that influences the brain, heart and facial highlights Kumar Jeetendra | January 21, 2021 Researchers at the National Institutes of Health have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart and facial features. Named linkage-specific-deubiquitylation-deficiency-induced embryonic defects syndrome (LINKED), it is caused by a mutated version of the OTUD5 gene, which interferes with key molecular actions in embryo development. The findings indicate …
Sloan Kettering Institute specialists offer news answer to 100-year-old malignancy secret Kumar Jeetendra | January 23, 2021 The year 2021 marks the 100th anniversary of a basic discovery that is taught in every biochemistry textbook. In 1921, German doctor Otto Warburg observed that cancer cells harvest energy from sugar sugar in a strangely inefficient manner: instead of”burn” it using cancer cells do what yeast do — they ferment it. This oxygen-independent process …
New device empowers study of SARS-CoV-2 mutant range by ultrasequencing Kumar Jeetendra | February 15, 2021 SARS-CoV-2 genome is three times larger than flu genome. Both consist of NRA molecules which mutate when replicate. It is essential to know its mutant spectrum, in other words, its”fingerprints”, to achieve an appropriate treatment that reduces its infectivity -the capacity of pathogens to invade organisms and cause infections-, since its composition of variables could …
Study maps design and system of a membrane enzyme that assumes part in inflammation, cancer Kumar Jeetendra | March 21, 2021 Most drugs operate via the membranes that surround the body’s cells. The analysis, which is printed in the journal Nature Communications, can make a significant contribution to the development of potential drugs. The cells’ equal to organs, the organelles, are enclosed by membranes. Embedded in the cell’s external and internal membranes are proteins that regulate …
Researchers discover proof that SARS-CoV-2 infects cells in the mouth Kumar Jeetendra | March 25, 2021 An international group of scientists has discovered evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. While it’s well known that the upper airways and lungs are primary sites of SARS-CoV-2 disease, there are clues the virus can infect cells in different parts of the body, like the digestive system, blood …
