UCL researchers distinguish new immunotherapy to battle hepatitis B infection Kumar Jeetendra | May 15, 2021 Researchers at UCL have identified a new immunotherapy to fight the hepatitis B virus (HBV), the most frequent cause of liver cancer in the world. The pioneering study used immune cells isolated directly from patient liver and tumour tissue, to demonstrate that targeting acyl-CoA:cholesterol acyltransferase (ACAT), an enzyme which helps to manage cholesterol levels in …
Scientists distinguish new compound that may forestall heart arrhythmia risk from basic drugs Kumar Jeetendra | May 16, 2021 Dozens of commonly used drugs, including antibiotics, antinausea and anticancer medications, have a potential side effect of lengthening the electrical event that causes regeneration, creating an irregular heartbeat, or cardiac arrhythmia called acquired Long QT syndrome. While safe in their current dosages, some of these drugs might have a more therapeutic benefit at higher doses, …
Researchers develop experimental direct-acting antiviral treatment to treat COVID-19 Kumar Jeetendra | May 18, 2021 An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19. Conventional antivirals reduce symptoms and help people recover earlier. Examples …
New medication like compound could adequately hinder a critical step in malaria parasite life cycle Kumar Jeetendra | May 19, 2021 Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a vital step in the malaria parasite life cycle and are working to develop this compound into a potential first of its type malaria treatment. While drugs and mosquito control have reduced levels of …
New radiopharmaceutical shows therapeutic efficacy in preclinical model of ovarian disease Kumar Jeetendra | June 12, 2021 Preclinical trials of a new radiopharmaceutical to treat ovarian cancer have produced effective results, dramatically restricting tumor growth and diminishing tumor mass. Designed especially for ovarian cancers that are resistant to conventional therapies, the new radiopharmaceutical could be produced in 25 minutes at reduced cost, which contributes to better efficiency compared with alternative procedures. This …
Ladies treated with fertility drugs don’t have expanded breast cancer risk, study shows Kumar Jeetendra | June 21, 2021 Drugs frequently used during fertility treatments to release eggs don’t increase the chance of developing breast cancer, new research has shown. Researchers from King’s College London, in partnership with King’s Fertility, analyzed studies between 1.8 million women undergoing fertility treatments. These women were followed up in studies for a normal period of 27 years and …
MRI screening and designated biopsies could diminish overdiagnoses of prostate malignant growth Kumar Jeetendra | July 10, 2021 Many countries do not have nationwide prostate-cancer screening. Current methods lead to overdiagnoses, unnecessary biopsies, and unnecessary biopsies. Researchers at Karolinska Institutet, Sweden, have published a new study in The New England Journal of Medicine. It shows that targeted biopsies and magnetic resonance imaging (MRI), could reduce overdiagnoses by up to half. These results were …
Analysts study the role of subnuclear NSrp70 in T cell-intervened adaptive immunity Kumar Jeetendra | July 15, 2021 T cell are part of the body’s immune response. The way proteins are spliced in their development and maturation determines how T cells can recognize different pathogens and mount defense against them. Scientists from Korea now highlight the role of NSrp70 in regulating maturation. This protein was previously found in T cells subnuclear space and …
Scientists test a library of lipid-based compounds to empower safe RNA drug delivery to Lungs Kumar Jeetendra | July 30, 2021 Japan’s Hokkaido University researchers created and tested a collection of lipid-based compounds in order to deliver RNA drugs safely and effectively to the lungs. The findings were published in Materials Horizons. The COVID-19 pandemic response made it all more familiar with RNA vaccines. These vaccines carry genetic code into the cells, which triggers the production …
New Stem cell conveying hydrogel could assist the heart with recuperating myocardial ischemia Kumar Jeetendra | August 11, 2021 When blood vessels that feed the heart become blocked, damage to the heart muscle can occur and this can affect cardiac function. By stimulating the formation of new blood vessels, a new stem-cell-carrying gel helps mice overcome this condition called myocardial Infarction. The stem cell delivery system was developed by scientists from Kansai University, Japan. …
Researchers develop another approach to grow little pancreas replicas Kumar Jeetendra | September 14, 2021 In collaboration with Cancer Research UK Manchester Institute scientists, engineers from MIT have created a new method to create tiny replicas of pancreas using healthy and cancerous pancreatic cell lines. These models could be used by researchers to test and develop potential treatments for pancreatic cancer. This is one of the most difficult types. Researchers …
Small molecule drug can weaken the triggers of neuroinflammation, preclinical review shows Kumar Jeetendra | September 24, 2021 Neuroinflammation may cause worse outcomes in cases of stroke, injuries to the brain or injury, and can increase the severity of neurodegenerative diseases such as ALS, Parkinson’s, or Alzheimer’s. This suggests that reducing neuroinflammation might be an exciting new method to treat neurological disorders and neuropathic pain caused by neuroinflammation. In a preclinical study , …
