Researchers utilize funtional test to quantify the impact of inhertited varient in BRCA2 acancer gene Kumar Jeetendra | February 21, 2021 Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variations in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS). The findings were published today in a study …
Scientists concentrate what the methylation of proteins means for various mitochondrial measures Kumar Jeetendra | February 21, 2021 Diseases of the cells’ energy supply can cause a range of serious ailments, but also appear to be connected to aging. More research is required on mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet reveals how an important molecule inside the mitochondria affects their function in mice and fruit …
Study discoveries help clarify the variety of cancers in various Li-Fraumeni patients Kumar Jeetendra | February 23, 2021 The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several kinds of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations. Recent studies suggest that some people with inherited p53 …
Retroviruses attacking the koala germline add to high malignant growth rates Kumar Jeetendra | February 26, 2021 Koalas are facing multiple ecological and health issues which threaten their survival. Together with habitat loss – accelerated by last year’s devastating bush fires — domestic dog attacks and road accidents, they suffer from fatal chlamydial infections and extremely high frequency of cancer. The results are reported in the journal Nature Communications. The koala retrovirus …
Researchers build up a basic strategy to make drug precursor Kumar Jeetendra | February 27, 2021 Save your silver! It’s better used for jewellery than as a catalyst for medication. Rice University scientists have developed a greatly simplified method to make fluoroketones, precursors for drug design and manufacture that typically demand a silver catalyst. Rice chemist Julian West and grad students Yen-Chu Lu and Helen Jordan introduced a procedure for the …
Genomic Data Commons offers the biggest asset in cancer genomics Kumar Jeetendra | February 27, 2021 The National Cancer Institute’s Genomic Data Commons (GDC), launched in 2016 by then-Vice President Joseph Biden and hosted at the University of Chicago, has become one of the largest and most widely used resources in cancer genomics, with over 3.3 petabytes of data from more than 65 jobs and more than 84,000 anonymized patient cases, …
Novel device can add or eliminate sugar from proteins Kumar Jeetendra | March 12, 2021 Sugar has been called “evil,” “toxic,” and “poison.” But the body needs sugars, also. Sugar molecules help cells recognize and fight germs and viruses, shuttle proteins from cell to cell, and make sure those proteins function. Too much or too small can give rise to a range of maladies, including neurodegenerative diseases like Alzheimer’s, diabetes, …
CN Bio presents the PhysioMimix™ OOC Multi-Organ Microphysiological System Kumar Jeetendra | March 17, 2021 CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS. The next-generation system unites CN Bio’s in vitro 3D liver model, whose phenotype and functions mimic that in vivo, with a range of other organs to …
FDA approves first AI based COVID-19 non-diagnostic screening Kumar Jeetendra | March 21, 2021 Now, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the first machine learning-based Coronavirus Disease 2019 (COVID-19) non-diagnostic testing apparatus that identifies certain biomarkers that are indicative of some kinds of conditions, such as hypercoagulation (a condition causing blood to clot more readily than normal). The Tiger Tech COVID Plus …
Study maps design and system of a membrane enzyme that assumes part in inflammation, cancer Kumar Jeetendra | March 21, 2021 Most drugs operate via the membranes that surround the body’s cells. The analysis, which is printed in the journal Nature Communications, can make a significant contribution to the development of potential drugs. The cells’ equal to organs, the organelles, are enclosed by membranes. Embedded in the cell’s external and internal membranes are proteins that regulate …
Bacteria residing within inside tumor cells can support malignant growth immunotherapy Kumar Jeetendra | March 22, 2021 Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. The study may also help clarify the connection between immunotherapy and the intestine microbiome, describing the findings of earlier research that the microbiome impacts the success of immunotherapy. Immunotherapy remedies of the last decade or so have dramatically improved healing …
Researcher find a gene mutation connected to schizophrenia Kumar Jeetendra | March 24, 2021 Researchers at The Feinstein Institutes for Medical Research, in collaboration with Columbia University, have identified a gene mutation that could result in schizophrenia, a chronic brain disease that affects nearly 1 percent of the planet’s inhabitants. The findings, published in today in Neuron, could lead to novel treatment strategies. The research group, headed by Todd …
