Scientists Targeting Stem Cell Therapy To Promote Personalized Medicine

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• Date: 29 Feb,2016

Researcher from Lieber Institute for Brain Development (LIBD) recently used group of cells derived from human skin to develop new tissue and organ may greatly support personalized medicine, the concern research recently appears ion PLOS Genetics.

The researcher used human derived skin to develop tissue and organ therefore cells are more vulnerable against environmental exposure. The researcher from Lieber Institute for Brain Development (LIBD) used fibroblast type of from dura mater of post mortem brain and compare with used skin samples on same individuale. The scientist reports identity of cells under microscope. This study widely support epigenetic and gene expression differences.

According to Researcher,

"These age-related changes are one of the first examples, to our knowledge, of significant age-related changes in a pure cell population that is many divisions from the original cells."

The results of this study suggests there are differences between skin derived cells and Dura cells from brain throughout life span which in turn supports field of personalized medicine.

The above story is for information purpose only for more information go through story source, the above story is titled Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age," was led by Andrew E. Jaffe, Ph.D. and is appears in recent edition of PLOS Genetics.

Journal References

Nikolay A. Ivanov, Ran Tao, Joshua G. Chenoweth, Anna Brandtjen, Michelle I. Mighdoll, John D. Genova, Ronald D. McKay, Yankai Jia, Daniel R. Weinberger, Joel E. Kleinman, Thomas M. Hyde, Andrew E. Jaffe. Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age. PLOS Genetics, 2016; 12 (2): e1005819 DOI: 10.1371/journal.pgen.1005819