Subscribe to our Newsletters !!
In the era of changing pharmaceutical innovation p
The pharmaceutical sector is on the cusp of a new
The Nobel Prize in Physiology or Medicine awarded
Shilpa Medicare – the full-service contract de
A few months b Pharma News
A few months b
Since it’s an ingredient in so many foods, you h
Dear Readers, Welcome to the latest issue of Micr
In the era of changing pharmaceutical innovation paradigms, microorganisms are still the unseen engineers of some of the most life-saving drugs known to humankind. Since the discovery of antibiotics and recombinant proteins to their production on a large scale, microbial fermentation has been the cornerstone of today’s biopharmaceutical industry.
Using the metabolic potential of bacteria, fungi, and actinomycetes, the pharmaceutical industry uses fermentation as a platform technology for the production of a vast range of therapeutic molecules, enzymes, and bioactive compounds with accuracy and scalability.
Microbial fermentation is the growth of microorganisms in a controlled environment to convert raw materials to useful products, based on enzymatic activity. The bioprocess is the basic process in the production of antibiotics, amino acids, hormones, vitamins, vaccines and biopolymers. Consistency, purity and high yields during the fermentation are important in pharmaceutical production. This involves having the right strain but also the right Culture Media that allows the best microbial growth and metabolite production. And here’s where TM Media’s specific fermentation media come into play.
TM Media, the microbiology brand of Titan Biotech Ltd, has been a trusted Culture Media manufacturer for more than 32 years. TM Media has a wide range of products containing over 2,500 formulations of Dehydrated Culture Media and convenient Ready-to-Use Culture Media. They have a variety of products, like Biological Media Bases, Lab Consumables & Equipments, Chemicals, Antibiotics Sensitivity Discs and many more to meet specific requirements in supporting microbial testing biotechnology and fermentation at any scale from R&D laboratories to full-scale production plants.
The formulations of TM Media are carefully designed to meet with global pharmacopoeia standards and have become a trusted option for researchers and quality teams in the pharmaceutical industry. Here are some of their major products that enable innovation and discovery in microbial fermentation.
The Fermentation Medium Base (TM 2076) is a highly flexible nutrient broth that can be used to grow a wide variety of organisms. It is enriched with balanced sources of carbon, nitrogen, vitamins, and minerals. This composition makes this medium a base medium that can be supplemented as needed with other components.
It is useful for seed culturing and fermentation parameter optimization in both antibiotic and enzyme production. This flexibility has made it the preferred option of bioprocess engineers to develop economical high-yield fermentation processes. Marine microbes are being recognized as a new resource for bioactive drug molecules and enzymes. The Marine Oxidation Fermentation Medium (TM 782) from TM Media simulates the conditions of the marine environment and allows growth of salt-loving or marine bacteria.
The medium is suitable for aerobic metabolism and may enable researchers to discover novel bioactive molecules with applications in anti-cancer, anti-inflammatory and anti-microbial drug research. Certain bioprocesses in the pharmaceutical industry involve the growth of fastidious microbes that require very particular nutrients.
The Fermentation Medium for Neisseria (TM 2077) is a defined medium for growth of Neisseria species, which are commonly used in the generation of vaccine antigens and in pathogen based applications. Its defined composition guarantees reproducible growth and metabolite production and it can be used for diagnostics and vaccine production, where nutrient limitation could be necessary to keep antigenic integrity.
TM Media’s Thioglycollate Broth with Liver Extract (TM 216) is a well-established base broth medium for the growth of anaerobic and microaerophilic bacteria applications in the pharmaceutical and biotechnology industries. Enriched with liver extract, this media facilitates the recovery of fastidious organisms.
It can be used for sterility testing, contamination investigations and fermentation processes with oxygen-sensitive bacteria. Along with their fermentation media, TM Media also provides a wide range of Biological Media Bases such as Veg. Be Extract powder, Maltose (Monohydrate) NRC Grade, Tryptone-D and many more essential substrates which are important for preparation of microbial growth media. These essential ingredients are excellent sources of amino acids, peptides and growth factors for a variety of microbial species. Its consistent nature and excellent nutrition make it vital in culture media formulations used in the fermentation industry in the production of vaccines and antibiotics.
The success of the microbial fermentation in pharmaceuticals is dependent on the right combination of nutrients, sterility and process control. Dehydrated and Ready-to-Use forms of TM Media’s fermentation Culture Media offer convenience, reproducibility, and compliance with regulatory requirements. Their Ready-to-Use Culture Media range is gamma-irradiated and triple-packed for sterility and to avoid any risk of contamination, which is an essential requirement in aseptic production environments. By promoting the growth of microbes from an incredibly diverse range of strains, TM Media provides the tools needed for revolutionizing drug discovery, improving strains and streamlining processes in microbial biotechnology.
The pharmaceutical sector keeps advancing with the increase of biotechnological tools; the production of drugs through microbial fermentation will continue to be a pillar of sustainable and cost-effective drug production. TM Media’s dedication to quality, consistency and scientific rigour allows microbiologists and bioprocess engineers to innovate with confidence. With revolutionary products such as the Fermentation Medium Base, Marine Oxidation Fermentation Medium and a range of specialised strain media, TM Media closes the gap between microbial potential and pharmaceutical accuracy, powering the future of biotech and microbial innovation.
