Surgery may expand length of endurance for metastatic breast malignant growth patients Kumar Jeetendra | December 28, 2020 They studied nearly 13,000 stage four breast cancer patients and found that those who had surgery as well as their other remedies had a survival advantage over those who had other therapies alone. Stage four breast cancer accounts for 6% of newly-diagnosed breast cancer cases. Systemic treatment, which may include treatments like chemotherapy, hormone therapies …
UH scientist attempting to recognize likely new therapeutic target for kidney sickness Kumar Jeetendra | January 14, 2021 In the past year, high serum suPAR levels also have been found to predict kidney and multiple organ failure in hospitalized patients with COVID-19. “FSGS is a particularly insidious kidney disease. In many patients, it inexorably leads to kidney failure and we don’t have much to offer to stop it, and worse still, in most …
Sulforaphane draws out life expectancy and healthspan of C. elegans through insulin/IGF-1 flagging Kumar Jeetendra | February 4, 2021 Aging-US released”Sulforaphane boosts C. elegans longevity and healthspan through DAF- 16/DAF-2 insulin/IGF-1 signaling” which reported that the broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its impact on healthspan and longevity are unclear. The writers used the C. elegans nematode version and fed the wildtype and 9 mutant strains ±sulforaphane. Sulforaphane increased the …
Altered lipids focus on the body’s endocannabinoid framework to control pain and inflammation Kumar Jeetendra | February 10, 2021 When modified using a process known as epoxidation, two naturally occurring lipids are converted to potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways which promote inflammation and pain, researchers report. These modified compounds, called epo-NA5HT and epo-NADA, have much stronger effects than the molecules from which they are derived, which also modulate …
Killing antibodies actuated by COVID-19 vaccines less successful against new variants Kumar Jeetendra | March 15, 2021 SARS-CoV-2, the virus that causes COVID-19, has mutated through the pandemic. New variants of this virus have arisen around the world, including variants that might possess increased capacity to spread or evade the immune system. Such variations have been identified in California, Denmark, the U.K., South Africa and Brazil/Japan. Recognizing how well the COVID-19 vaccines …
Researchers discover proof that SARS-CoV-2 infects cells in the mouth Kumar Jeetendra | March 25, 2021 An international group of scientists has discovered evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. While it’s well known that the upper airways and lungs are primary sites of SARS-CoV-2 disease, there are clues the virus can infect cells in different parts of the body, like the digestive system, blood …
New hereditarily encoded sensor recognizes drugs of abuse Kumar Jeetendra | April 29, 2021 A genetically encoded sensor to detect hallucinogenic compounds has been developed by researchers at the University of California, Davis. Named psychLight, the sensor could be used in discovering new treatments for mental illness, in neuroscience research and to detect drugs of abuse. The work is published April 28 in the journal Cell. Compounds associated with …
Immunotherapy treatments for nephrological autoimmune illnesses may help treat serious Coronavirus Kumar Jeetendra | June 8, 2021 Various viruses and bacteria have been known to cause autoimmune diseases where there’s such a predisposition. This phenomenon also seems to play a major part SARS-CoV-2, especially in severe courses. The body’s own immune cells are activated, with the formation of autoantibodies that attack the body’s own healthy cell structures (proteins, autoantigens); deposits of immune …
Castration of male sheep eases back DNA maturing Kumar Jeetendra | July 6, 2021 We all know that women live longer lives than men. If we told you that there were one way to prolong your life, would you listen? Researchers from University of Otago and collaborators from the United States published a study in ELife today. It showed that castration of male sheep slows down DNA’s aging and …
Study recognizes specific immune cells that shape inhibitory neurons to control mind wiring Kumar Jeetendra | July 7, 2021 Every second our brains are exposed to a variety of signals, from the barking of a puppy to raindrops hitting the windows, and everything in between. Most of the time we ignore insignificant cues like the buzzing of a fly or the gentle rustle of leaves in a tree. We pay attention to the more …
Scientists find how Rift Valley fever virus enters cells Kumar Jeetendra | September 24, 2021 Rift Valley fever virus causes economically tragic hemorrhagic outbreaks in livestock, including cattle, goats, and sheep. The mosquito-borne infections can lead to the spread of infection to people who work with animals that are dying or dead often causing many human infections as well as many deaths. Rift Valley fever, for which there isn’t a …
Novel antibody candidate shows powerful binding to different SARS-CoV-2 variant mutations Kumar Jeetendra | September 25, 2021 Twist Bioscience Corporation today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19. The Coronavirus Immunotherapy Consortium (CoVIC) is an academic-industry-non-profit …
