New technology May Raise the quality of stem cells Found in regenerative medicine Kumar Jeetendra | July 8, 2020 Stem cells have been holding great promise for regenerative medicine for ages. In the last decade, many studies have revealed this form of cell, which in Spanish is called”mother cell” due to its ability to contribute to various different cell types, may be applied in regenerative medicine to diseases such as muscle and nervous system …
Test mRNA-based COVID-19 immunization evokes defensive safe reactions in animals Kumar Jeetendra | July 25, 2020 Two injections of this vaccine were enough to induce robust immunity, completely preventing SARS-CoV-2 infection in mice. MRNA-based vaccines are all attractive options for protecting against SARS-CoV-2 because they may be quickly designed and manufactured at a huge scale within weeks. Moreover, preclinical studies have shown that mRNA-based vaccines cause potent and broadly protective immune …
Oregon scientists uncover sub-atomic instruments that produce DNA harm in sperm Kumar Jeetendra | October 25, 2020 University of Oregon biologists have used the model organism Caenorhabditis elegans to identify molecular mechanisms that produce DNA damage in sperm and contribute to male infertility following exposure to heat. In humans, the optimal temperature for sperm production is just below body temperature, in a range of approximately 90-95 degrees F. Human studies have found …
Engineered counter acting agent may forestall Covid from contaminating human cells Kumar Jeetendra | November 4, 2020 By screening hundreds of artificial antibodies, researchers at Karolinska Institutet in Sweden and EMBL Hamburg in Germany have identified an antibody that may prevent the new coronavirus from infecting human cells. The analysis, which is printed in the journal Nature Communications, also reveals how electrons can be quickly generated in the event of future pandemics. …
Researchers utilize human stem cells and bioengineered platform to construct entire working thymus Kumar Jeetendra | December 11, 2020 Their work is an important step towards having the ability to build artificial thymi that could be utilised as transplants. The thymus is an organ in the chest where T lymphocytes, which play a vital role in the immune system, mature. If the thymus doesn’t work properly or doesn’t form during foetal development in the …
Hematoxylin compounds can specifically kill CALR mutant cancer cells Kumar Jeetendra | December 11, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Researchers of the research team of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
Hematoxylin compounds can specifically kill CALR freak disease cells Kumar Jeetendra | December 20, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
Scientists grow new framework for direct location of SARS-CoV-2 in aerosols Kumar Jeetendra | December 28, 2020 Researchers in the Polytechnic University of Valencia (UPV), in collaboration with specialists from the University of Valencia (UV), have produced a new system based on a high-sensitivity mass biosensor that continuously monitors signals for the immediate detection of SARS-CoV-2 in environmental aerosols. The device, in prototype stage, makes it possible to appraise the quality of …
Scientists disentangle the cycle that makes virus irresistible Kumar Jeetendra | January 9, 2021 Researchers have for the first time identified how viruses like the poliovirus and the common cold virus’package up’ their genetic code, allowing them to infect cells. The findings, published today (Friday, 8 January) in the journal PLOS Pathogens by a team from the Universities of Leeds and York, open up the possibility that medication or …
Sulforaphane draws out life expectancy and healthspan of C. elegans through insulin/IGF-1 flagging Kumar Jeetendra | February 4, 2021 Aging-US released”Sulforaphane boosts C. elegans longevity and healthspan through DAF- 16/DAF-2 insulin/IGF-1 signaling” which reported that the broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its impact on healthspan and longevity are unclear. The writers used the C. elegans nematode version and fed the wildtype and 9 mutant strains ±sulforaphane. Sulforaphane increased the …
New device empowers study of SARS-CoV-2 mutant range by ultrasequencing Kumar Jeetendra | February 15, 2021 SARS-CoV-2 genome is three times larger than flu genome. Both consist of NRA molecules which mutate when replicate. It is essential to know its mutant spectrum, in other words, its”fingerprints”, to achieve an appropriate treatment that reduces its infectivity -the capacity of pathogens to invade organisms and cause infections-, since its composition of variables could …
Researchers describe the systems that manage embryonic stem cells Kumar Jeetendra | March 26, 2021 Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have clarified the mechanisms, unknown to date, included in maintaining embryonic stem cells in the best possible condition for their use in regenerative medicine. The results, published in Nature Communications, helps to find novel stem-cell therapies for …
