Hematoxylin compounds can specifically kill CALR mutant cancer cells Kumar Jeetendra | December 11, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Researchers of the research team of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
IGC analysts get three out of six European Research Council grants Kumar Jeetendra | December 11, 2020 Since the establishment of the European Research Council in 2008, the IGC has secured 17 of the competitive grants (7 Beginning, 8 Consolidator and two Advanced). In 2021, with the beginning of the new grants awarded this month, it will have ten active grants. The year of 2020 marks a total of 327 researchers chosen …
Study: Most pregnant patients tested positive for Covid were asymptomatic Kumar Jeetendra | December 12, 2020 The pregnant patients who tested positive for the coronavirus were also more likely than those who tested negative to identify as Hispanic and report their primary language as Spanish. In a retrospective cross-sectional analysis of worldwide screenings for SARS-Cov-2, the virus which causes COVID-19, implemented in the labor and delivery unit of Elmhurst Hospital in …
New information shows empowering results for patients with neuro-degenerative blinding eye illness Kumar Jeetendra | December 16, 2020 New data published in the Journal Science Translational Medicine shows encouraging results in a worldwide clinical trial for patients diagnosed with the neuro-degenerative blinding eye disease; Leber Hereditary Optic Neuropathy (LHON. The disease is an inherited type of vision loss estimated to affect 1 in 30,000 to 50,000 individuals. LHON most often afflicts individuals with …
Skin may assist with foreseeing future heart issues Kumar Jeetendra | December 17, 2020 Our skin informs us when we have spent too much time in sunlight or when the dry air of winter has sucked away too much moisture. Now Jefferson researchers find that the skin may also foretell problems unrelated to the protective barrier. An international group of researchers headed by Jouni Uitto, MD, PhD, a Professor …
new cGMP plasmid DNA manufacturing facility construction announced by Thermo Fisher Kumar Jeetendra | December 18, 2020 Thermo Fisher Scientific, the world leader in serving science, today announced the construction of a new cGMP plasmid DNA manufacturing facility in Carlsbad, Calif. The site will expand the company’s clinical and commercial capabilities for cGMP plasmid DNA used as a critical raw material to develop and manufacture cell and gene-based therapies including life-saving cancer …
Study recognizes biomarker gene mark that demonstrates likely liver toxicity Kumar Jeetendra | December 19, 2020 When agrochemical and pharmaceutical companies develop new products, they must test extensively for potential toxicity before obtaining regulatory approval. This testing usually involves lengthy and expensive animal research. A research team at University of Illinois has developed a gene biomarker identification technique that cuts the testing process down to a couple of days while still …
Scientists found and describe two contagious species unexpectedly Kumar Jeetendra | December 20, 2020 University of Copenhagen scientists have found and described two fungal species for the first time. The fungi infect adult flies and then create a hole in the gut of the hosts’ bodies. Infected flies then buzz around days as the fungi devour them from within and eject fungal spores from these holes in their bodies. …
Hematoxylin compounds can specifically kill CALR freak disease cells Kumar Jeetendra | December 20, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
Trinity crew uncovers mutations connected with early onset dementia Kumar Jeetendra | December 22, 2020 Researchers at Trinity College Dublin today announced a significant advance in our knowledge of an early onset form of dementia which may also advance our understanding of conditions such as Alzheimer’s disease. Adult onset Leukoencephalopathy with axonal Spheroids and Pigmented glia (ALSP) is an ultra-rare condition characterized by mutations in a gene named Colony stimulating …
New drug mixture improves blood glucose manipulate and weight reduction in mice Kumar Jeetendra | December 23, 2020 Scientists have demonstrated that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published today in eLife. The results pave the way for clinical trials of this new drug combination as a more successful long-term remedy for countless individuals with …
Study clarifies the impact of getting old on hematopoietic stem cells Kumar Jeetendra | December 25, 2020 By shifting mouse elderly hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was shown that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem cells. On the other hand, the function of elderly HSCs failed to recover in the young bone marrow …
