Skin may assist with foreseeing future heart issues Kumar Jeetendra | December 17, 2020 Our skin informs us when we have spent too much time in sunlight or when the dry air of winter has sucked away too much moisture. Now Jefferson researchers find that the skin may also foretell problems unrelated to the protective barrier. An international group of researchers headed by Jouni Uitto, MD, PhD, a Professor …
Pig stem cells offer another approach to develop human organs for transplantation Kumar Jeetendra | December 18, 2020 In a new paper published in Stem Cell Reports, Bhanu Telugu and co-inventor Chi-Hun Park of the University of Maryland (UMD) Department of Animal and Avian Sciences show for the first time that newly generated stem cells from cows, when injected into embryos, contributed to the growth of only the organ of interest (the embryonic …
Study recognizes biomarker gene mark that demonstrates likely liver toxicity Kumar Jeetendra | December 19, 2020 When agrochemical and pharmaceutical companies develop new products, they must test extensively for potential toxicity before obtaining regulatory approval. This testing usually involves lengthy and expensive animal research. A research team at University of Illinois has developed a gene biomarker identification technique that cuts the testing process down to a couple of days while still …
FDA favors first conventional glucagon for injection to treat extreme hypoglycemia Kumar Jeetendra | December 29, 2020 Today, the U.S. Food and Drug Administration approved the first generic of glucagon for injection USP, 1 mg/vial packed in an emergency kit, for the treatment of severe hypoglycemia (very low blood sugar), which may occur in patients with diabetes mellitus. The drug is also indicated as a diagnostic aid in the radiologic examination of …
FDA-endorsed COVID-19 medication should be utilized warily, says UC researcher Kumar Jeetendra | January 4, 2021 While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics continue to be necessary to treat hepatitis patients. One of these treatments, remdesivir, is the first and only antiviral agent of its type the U.S. Food and Drug Administration (FDA) has approved so far for COVID-19. Research at the University …
Recently recognized supplement helps the gut review earlier diseases and execute attacking bacteria Kumar Jeetendra | January 17, 2021 Scientists studying the body’s natural defenses against bacterial disease have identified a nutritional supplement –taurine–that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn). The finding, published in the journal Cell by scientists from five institutes of the National Institutes of Health, could help efforts seeking alternatives to antibiotics. …
Putatively juvenile dendritic cells may actuate hearty resistant reactions in young children Kumar Jeetendra | January 20, 2021 A study by Ludwig-Maximilians-Universitaet (LMU) in Munich researchers demonstrates that putatively immature dendritic cells found in young children are able to induce strong immune responses. Dendritic cells are a vital component of the innate immune system, which represents the body’s first line of defense against infectious agents and tumor cells. Their job is to trigger …
Pancreatic β cell-inferred exosomal miR-29s control glucose homeostasis Kumar Jeetendra | January 24, 2021 In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang’s team at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig’s group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in reaction to high levels of free fatty acids (FFAs). Formerly, Chen-Yu Zhang’s team identified …
Study shows why children of obese moms have inclination to create metabolic illnesses Kumar Jeetendra | January 27, 2021 A Brazilian study published in the journal Molecular Human Reproduction helps understand why overweight mothers often have children with a propensity to develop metabolic disease during their lifetime, according to previous research. According to the authors,”transgenerational transmission of metabolic disorders” may be associated with Mfn2 deficiency in the mother’s oocytes (immature eggs). Mfn2 refers to …
Novel finding could prompt better medicines for Type 1 and Type 2 diabetes Kumar Jeetendra | February 13, 2021 Monash University researchers have discovered the barrier to β-cell (beta mobile ) regeneration which could pave the way for improved treatments for diabetes and diseases that involve organ and tissue damage. The human body does not repair itself very well, with our liver the only organ that can regenerate economically. We have limited capacity to …
Researchers build up a basic strategy to make drug precursor Kumar Jeetendra | February 27, 2021 Save your silver! It’s better used for jewellery than as a catalyst for medication. Rice University scientists have developed a greatly simplified method to make fluoroketones, precursors for drug design and manufacture that typically demand a silver catalyst. Rice chemist Julian West and grad students Yen-Chu Lu and Helen Jordan introduced a procedure for the …
CN Bio presents the PhysioMimix™ OOC Multi-Organ Microphysiological System Kumar Jeetendra | March 17, 2021 CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS. The next-generation system unites CN Bio’s in vitro 3D liver model, whose phenotype and functions mimic that in vivo, with a range of other organs to …
