New initiative identifies key parameters Inherent effective anti-tumor immunity Kumar Jeetendra | October 10, 2020 Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies. Targeting the”right” neoantigens – at a cancer vaccine or a cell treatment – has the promise to eliminate a patient’s cancer with minimal side effects. But countless mutations can exist in …
Analysts expect to recognize illness resistance instruments in sepsis patients Kumar Jeetendra | October 16, 2020 Sepsis is estimated to cause 11 million deaths each year in the world. Its treatment is based on the use of antibiotics and organ support measures, but many times it fails because of unsuccessful attempts at controlling the immune reaction. Surviving a serious infection requires the activation of mechanisms both of resistance. This reduce the …
CBD could lessen lung harm brought about by COVID-19 Kumar Jeetendra | October 19, 2020 One way CBD appears to reduce the”cytokine storm” that damages the lungs and kills many individuals with COVID-19 is by enabling an increase in levels of a natural peptide called apelin, which is proven to reduce inflammation and whose levels are dramatically reduced in the face of this storm. Dental College of Georgia and Medical …
Myeloid cells can smother insusceptible reaction, advance cerebrum metastasis Kumar Jeetendra | October 28, 2020 Scientists have long thought that the brain protects itself from an aggressive immune response to keep inflammation down. However, that evolutionary management may work against it when a cancer cell tries to spread to the brain, researchers at the University of Notre Dame have found. In recently published research in the journal Cell, researchers showed …
Drug used to control pulse may improve malignant growth patients’ reaction to immunotherapy Kumar Jeetendra | November 1, 2020 The exact same biochemical triggers which spur a”flight or fight” reaction once we encounter threats may help tumor cells to thrive. A group of researchers from Roswell Park Comprehensive Cancer Center is looking at ways to interrupt that dynamic so that cancer therapies can be effective. Their latest work, published today in Clinical Cancer Research, …
Microorganisms in the lungs could impact lung cancer progression and prognosis Kumar Jeetendra | November 11, 2020 Bottom Line: Enrichment of the lungs with oral commensal microbes has been correlated with advanced stage disease, worse prognosis, and tumor progression in patients with lung cancer. Journal in Which the research was Published: Cancer Discovery, a journal of the American Association for Cancer Research Author: Leopoldo Segal, MD, director of the Lung Microbiome Program, …
New SARS-CoV-2 IgM assay introduced by Beckman Coulter in countries accepting the CE Mark Kumar Jeetendra | November 12, 2020 Beckman Coulter, a medical diagnostics pioneer, today announced the launching of its accessibility SARS-CoV-2 Immunoglobulin M (IgM) assay in countries accepting the CE Mark. The brand new IgM antibody test revealed 99.9% specificity with 1,400 negative trials and 100% sensitivity at >18 times post symptom onset and post positive PCR. Beckman Coulter’s IgM assay is …
Researchers distinguish systems behind inflammasome initiation by fungal pathogens Kumar Jeetendra | December 3, 2020 Researchers at St. Jude Children’s Research Hospital have identified the mechanisms behind inflammasome activation driven by infection with the fungal pathogen Aspergillus fumigatus. Fungal infection, especially with A. fumigatus, is a leading cause of infection-associated deaths in people with compromised immune systems. The work provides clues to a potential therapeutic approach for treating infectious and …
Study distinguishes protein as likely restorative objective for leishmaniasis vaccine Kumar Jeetendra | December 12, 2020 According to the results of research led by the Complutense University of Madrid (UCM), among the various strategies deployed by the Leishmania parasite to avoid tripping the human immune system is to trigger the SHP-1 protein. The parasite does this by secreting a molecule capable of interacting with the Mincle receptor expressed by antigen-presenting dendritic …
Researchers grow new serological assay for discovery of SARS-CoV-2 antibodies Kumar Jeetendra | December 13, 2020 Researchers at UC Santa Cruz have developed a novel serological assay for the detection of antibodies to SARS-CoV-2, the coronavirus which causes COVID-19. Rebecca DuBois, associate professor of biomolecular engineering at UC Santa Cruz, said the new method her staff developed is as accurate as the most dependable antibody tests now available, but is less …
Researchers pick out new weapon to war the growing tide of antibiotic-resistant bacteria Kumar Jeetendra | December 24, 2020 As scientists around the globe wage war against a publication, deadly virus, one University of Colorado Boulder laboratory is working on new weapons to battle a distinct microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unattended, could kill an estimated 10 million people annually by 2050. In a paper published Friday in …
Boosting a characteristic cell cycle could bring down ventilator-related lung damage Kumar Jeetendra | January 12, 2021 An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is very likely to cause further lung damage. In a new study, scientists identified a molecule that’s produced by immune cells during mechanical ventilation to try to decrease …
