Study maps design and system of a membrane enzyme that assumes part in inflammation, cancer Kumar Jeetendra | March 21, 2021 Most drugs operate via the membranes that surround the body’s cells. The analysis, which is printed in the journal Nature Communications, can make a significant contribution to the development of potential drugs. The cells’ equal to organs, the organelles, are enclosed by membranes. Embedded in the cell’s external and internal membranes are proteins that regulate …
Researchers describe the systems that manage embryonic stem cells Kumar Jeetendra | March 26, 2021 Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have clarified the mechanisms, unknown to date, included in maintaining embryonic stem cells in the best possible condition for their use in regenerative medicine. The results, published in Nature Communications, helps to find novel stem-cell therapies for …
Scientists recognize neural circuit associated with reciprocally controlling weight gain and despondency Kumar Jeetendra | March 27, 2021 Research has found that obesity and mental disorders such as depression and anxiety seem to often go together. Researchers at Baylor College of Medicine and cooperating institutions are providing new insights into this association by identifying and characterizing a novel neural circuit that mediates the reciprocal control of feeding and mental conditions in mouse models. …
Scientists use genetics to recognize likely drugs for early administration of COVID-19 Kumar Jeetendra | April 12, 2021 A new study using human genetics indicates researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages. The findings appeared online in the journal Nature Medicine at March 2021. The purpose is to identify present drugs, either FDA-approved or in clinical development for other conditions, that can …
Study offers a non-obtrusive avenue for monitoring buildings for COVID-19 Kumar Jeetendra | April 14, 2021 A study done in rooms where COVID-19 patients were isolated reveals that the virus’s RNA – part of the genetic material inside a virus – can persist up to a month in dust. The study did not evaluate whether dust may transmit the virus to people. It could, however, offer another option for monitoring COVID-19 …
Genetic variants that sway protein restricting in immune cells can cause autoimmune disease Kumar Jeetendra | April 17, 2021 Certain genetic variants that cause modified protein binding in immune cells, are also seen in people at high risk of some autoimmune diseases, new research has found. Researchers from the Wellcome Sanger Institute, Josep Carreras Leukaemia Research Institute in Spain, and the MRC London Institute of Medical Sciences (LMS) discovered that specific genetic variants, which …
FDA supports new medication for therapy of adults with chronic kidney infection Kumar Jeetendra | May 1, 2021 Today, the U.S. Food and Drug Administration accepted Farxiga (dapagliflozin) oral tablets to decrease the risk of kidney function decline, kidney failure, cardiovascular death and hospitalization for heart failure in adults with chronic kidney disease who are at risk of disease progression. Chronic kidney disease occurs when the kidneys are damaged and can’t filter blood …
A solitary archaeal compound can create a spectacular scope of regular and non-common cardiolipins Kumar Jeetendra | May 7, 2021 Cells of all life forms are surrounded by a membrane that’s made of phospholipids. One of them are the cardiolipins, which form another class due to their distinctive structure. When studying the enzyme that’s responsible for generating cardiolipins in archaea (single-cell organisms that constitute a separate domain of life), biochemists at the University of Groningen …
Researchers examine signal necrotic cells that prompt phagocytic cells to overwhelm the dying cell Kumar Jeetendra | May 8, 2021 As people keep their homes clean and clutter in check, a crew of cells within the body is in charge of clearing the waste that the body generates, including cells that are dying. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means’eating cells’ “Phagocytosis is quite important for the body’s …
Scientists distinguish new compound that may forestall heart arrhythmia risk from basic drugs Kumar Jeetendra | May 16, 2021 Dozens of commonly used drugs, including antibiotics, antinausea and anticancer medications, have a potential side effect of lengthening the electrical event that causes regeneration, creating an irregular heartbeat, or cardiac arrhythmia called acquired Long QT syndrome. While safe in their current dosages, some of these drugs might have a more therapeutic benefit at higher doses, …
New medication like compound could adequately hinder a critical step in malaria parasite life cycle Kumar Jeetendra | May 19, 2021 Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a vital step in the malaria parasite life cycle and are working to develop this compound into a potential first of its type malaria treatment. While drugs and mosquito control have reduced levels of …
Immunotherapy treatments for nephrological autoimmune illnesses may help treat serious Coronavirus Kumar Jeetendra | June 8, 2021 Various viruses and bacteria have been known to cause autoimmune diseases where there’s such a predisposition. This phenomenon also seems to play a major part SARS-CoV-2, especially in severe courses. The body’s own immune cells are activated, with the formation of autoantibodies that attack the body’s own healthy cell structures (proteins, autoantigens); deposits of immune …
