New UCLA-formed gadget moves mitochondria into at least 100,000 or more beneficiary cells Kumar Jeetendra | January 1, 2021 Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput way of transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders. A study, published …
Scientists disentangle the cycle that makes virus irresistible Kumar Jeetendra | January 9, 2021 Researchers have for the first time identified how viruses like the poliovirus and the common cold virus’package up’ their genetic code, allowing them to infect cells. The findings, published today (Friday, 8 January) in the journal PLOS Pathogens by a team from the Universities of Leeds and York, open up the possibility that medication or …
Gene therapy can viably treat mice with tuberous sclerosis complex, shows study Kumar Jeetendra | January 9, 2021 Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in several organs of the body, have limited treatment choices. A team led by investigators at Massachusetts General Hospital (MGH) has shown that gene therapy can effectively treat mice that express one of the mutated genes that cause the disease. …
FDA cautions medical services suppliers and clinical lab staff about SARS-CoV-2 viral transformation Kumar Jeetendra | January 10, 2021 The U.S. Food and Drug Administration is alerting clinical laboratory staff and health care providers that the FDA is monitoring the potential effect of viral mutations, including an emerging version from the United Kingdom known as the B.1.1.7 variant, on approved SARS-CoV-2 molecular tests, which false negative results can occur with almost any molecular test …
Biomarkers can foresee how hereditarily identical cells act distinctively under pressure Kumar Jeetendra | January 10, 2021 A set of biomarkers not traditionally associated with cell fate can accurately forecast how genetically identical cells behave differently under pressure, according to a UT Southwestern study. The findings, published by Cell Reports as a Dec. 1 cover story, could eventually result in more predictable responses to pharmaceutical remedies. Groups of the same types of …
Analysts recognize interface among ALS and collection of DNA-RNA hybrids in the genome Kumar Jeetendra | January 13, 2021 Researchers from the University of Seville and the University of Pavia have identified a connection between Amyotrophic Lateral Sclerosis (ALS) and the accumulation of DNA-RNA hybrids in the genome. The accumulation of these hybrids causes increased genomic damage and boosts genetic instability. This finding will make it possible to better understand the molecular basis of …
The Cancer Microbiome Atlas gives more clear picture of microbiota living in organs Kumar Jeetendra | January 14, 2021 Biomedical engineers at Duke University have devised an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). With a clearer picture of the microbiota living in a variety of organs in both healthy and cancerous states, researchers will now have the ability to find new biomarkers of disease and better understand …
Researchers develop insect sex pheromones in transgenic camelina plant for maintainable pest control Kumar Jeetendra | January 15, 2021 The camelina plant, a source of cooking oil for centuries, is on its way toward revolutionizing pest management in agriculture. Researchers at ISCA, Inc., a green agtech firm based in Riverside, Calif., and their collaborators in Sweden have “grown” insect sex pheromone precursors in genetically modified strains of camelina plants, creating a low-cost source of …
Researchers produce first African lion in-vitro embryos after vitrification of juvenile oocytes Kumar Jeetendra | January 18, 2021 A team of scientists from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) in Germany, Givskud Zoo – Zootopia in Denmark and the University of Milan in Italy succeeded in producing the very first African lion in-vitro embryos after the vitrification of immature oocytes. For this specific method of cryopreservation, oocytes are collected right …
Inflammation may add to the determination of C. diff disease, shows study Kumar Jeetendra | January 19, 2021 A new study from North Carolina State University indicates that the inflammation brought on by Clostridioides difficile (C. diff) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for competing bacteria and supplying nutrients that enable C. diff to thrive. C. diff is a bacterium that causes diarrhea, often with severe …
Research finds new proof about the systems controlling skin repair and regeneration Kumar Jeetendra | January 19, 2021 As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has discovered new evidence deep within the skin about the mechanisms controlling skin renewal and repair. Skin’s barrier function gives it the unique ability to fight winter woes and keep …
Bacteria responsible for seafood related stomach disturbs can go torpid and “wake up” Kumar Jeetendra | January 20, 2021 Vibrio parahaemolyticus is a marine bacterium that can lead to gastroenteritis in humans when eaten in raw or undercooked shellfish such as oysters and mussels. Some of these bacteria have the ability to turn dormant in poor growth conditions such as cold temperatures – and can stay in that state of hibernation for long periods …
