Blood vessel deformities start in vein cells Kumar Jeetendra | November 3, 2020 In the condition called cavernoma, lesions appear in a cluster of blood vessels in the brain, spinal cord or retina. Researchers from Uppsala University can now reveal, at molecular level, these changes originate in vein cells. This new understanding of the condition creates possibility of developing better treatments for patients. The study was published in …
Study uncovers a quality answerable for anthraquinone synthesis in plants Kumar Jeetendra | November 25, 2020 Anthraquinones are a class of naturally occurring chemicals prized for their medicinal properties, as well as for other programs, including ecologically friendly dyes. Despite broad interest, the mechanism by which plants produce them has remained shrouded in mystery until today. New work from an international group of scientists including Carnegie’s Sue Rhee shows a gene …
CRISPR-based test could give fast, affordable testing to help control COVID-19 spread Kumar Jeetendra | December 7, 2020 Imagine swabbing your nostrils, putting the swab in a device, and obtaining a read-out on your mobile phone in 15 to 30 minutes which tells you if you’re infected with the COVID-19 virus. This has been the vision for a group of scientists at Gladstone Institutes, University of California, Berkeley (UC Berkeley), and University of …
Hematoxylin compounds can specifically kill CALR mutant cancer cells Kumar Jeetendra | December 11, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Researchers of the research team of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
IGC analysts get three out of six European Research Council grants Kumar Jeetendra | December 11, 2020 Since the establishment of the European Research Council in 2008, the IGC has secured 17 of the competitive grants (7 Beginning, 8 Consolidator and two Advanced). In 2021, with the beginning of the new grants awarded this month, it will have ten active grants. The year of 2020 marks a total of 327 researchers chosen …
Researchers grow new serological assay for discovery of SARS-CoV-2 antibodies Kumar Jeetendra | December 13, 2020 Researchers at UC Santa Cruz have developed a novel serological assay for the detection of antibodies to SARS-CoV-2, the coronavirus which causes COVID-19. Rebecca DuBois, associate professor of biomolecular engineering at UC Santa Cruz, said the new method her staff developed is as accurate as the most dependable antibody tests now available, but is less …
Active enzymes are expected to open full advantages of Vitamin A in carrots Kumar Jeetendra | December 14, 2020 Carrots are a good source of beta-carotene, which is a precursor of vitamin A. But to get the full health benefits of this superfood, you want an active enzyme to produce this vitamin. Studies with mice and humans reveal the conversion of beta-carotene to vitamin A reduces”bad” cholesterol in the blood. Therefore, beta-carotene can help …
First enzyme driven biocatalytic creation of nucleic acid structure blocks Kumar Jeetendra | December 15, 2020 Researchers in TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of lipoic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics. Because of this COVID 19 pandemic and the related intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is undergoing an enormous increase in …
Skin may assist with foreseeing future heart issues Kumar Jeetendra | December 17, 2020 Our skin informs us when we have spent too much time in sunlight or when the dry air of winter has sucked away too much moisture. Now Jefferson researchers find that the skin may also foretell problems unrelated to the protective barrier. An international group of researchers headed by Jouni Uitto, MD, PhD, a Professor …
Another way to deal with distinguish genomic areas in our cerebrum that add to make us human Kumar Jeetendra | December 17, 2020 With just 1% gap, the human and chimpanzee protein-coding genomes are remarkably similar. Knowing the biological characteristics that make us human is a part of a fascinating and intensely debated line of study. The paper is printed in Science Advances. Gene expression, not gene arrangement To describe what sets human besides their ape relatives, researchers …
Hematoxylin compounds can specifically kill CALR freak disease cells Kumar Jeetendra | December 20, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
Polygenic threat ratings from multi-populace information should enhance IBD predictions Kumar Jeetendra | December 25, 2020 Using genetic data from nearly 30,000 individuals, Mount Sinai researchers have assembled hazard scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn’s disease and ulcerative colitis. The research was published in Gastroenterology on December 24. The researchers found that polygenic risk scores, …
