Researchers discover proof that SARS-CoV-2 infects cells in the mouth Kumar Jeetendra | March 25, 2021 An international group of scientists has discovered evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. While it’s well known that the upper airways and lungs are primary sites of SARS-CoV-2 disease, there are clues the virus can infect cells in different parts of the body, like the digestive system, blood …
Researchers describe the systems that manage embryonic stem cells Kumar Jeetendra | March 26, 2021 Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have clarified the mechanisms, unknown to date, included in maintaining embryonic stem cells in the best possible condition for their use in regenerative medicine. The results, published in Nature Communications, helps to find novel stem-cell therapies for …
Scientists recognize neural circuit associated with reciprocally controlling weight gain and despondency Kumar Jeetendra | March 27, 2021 Research has found that obesity and mental disorders such as depression and anxiety seem to often go together. Researchers at Baylor College of Medicine and cooperating institutions are providing new insights into this association by identifying and characterizing a novel neural circuit that mediates the reciprocal control of feeding and mental conditions in mouse models. …
Small SARS-CoV-2 protein may have huge ramifications for future COVID-19 medicines Kumar Jeetendra | April 12, 2021 A very small protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future therapies, according to a team of Penn State researchers. Using a novel toolkit of approaches, the scientists uncovered the first full structure of the Nucleocapsid (N) protein and discovered how antibodies from COVID-19 patients interact with …
Study assesses stem cells’ capacity to forestall significant reason for death in preterm newborn Kumar Jeetendra | April 21, 2021 A phase 2 clinical trial whose results were published today in STEM CELLS Translational Medicine might point to a way to conquer bronchopulmonary dysplasia (BPD), a significant cause of death in preterm infants. The study, conducted by researchers at Samsung Medical Center, Sungkyunkwan University and Asan Medical Center Children’s Hospital in Seoul, evaluates the efficacy …
New expected objective for treating metastasized oral malignant melanoma in dogs Kumar Jeetendra | April 23, 2021 Scientists have shown that the biological molecule PD-L1 is a possible target for the treatment of metastasized oral malignant melanoma in dogs. There are a number of cancers that affect dogs, but there are far fewer diagnosis and treatment options for these canine cancers. However, because dogs and humans are both mammals, it is very …
New stage helps non-specialists use AI to examine microscopy pictures Kumar Jeetendra | April 24, 2021 A new, publicly available platform helps non-experts utilize artificial intelligence to examine microscopy images. The platform has been developed at Åbo Akademi University in Finland and Instituto Gulbenkian de Ciência, Portugal, and will be of big help in research and diagnostics using modern day microscopes. Software using artificial intelligence, AI, is revolutionizing how microscopy images …
Researchers examine how oxygen radicals secure against cancer Kumar Jeetendra | April 26, 2021 Initially, oxygen radicals – reactive oxygen species, or ROS for short – were thought of as exclusively harmful in the body. They’re produced, by way of example, by smoking or UV radiation. Because of their high reactivity, they could damage many important molecules in cells, including the hereditary molecule DNA. As a result, there’s a …
Novel platform has potential to detect many disease-related biomarkers in just one test Kumar Jeetendra | April 28, 2021 Most conventional molecular diagnostics usually detect only one disease-related biomarker. Fantastic examples are the PCR tests now used to diagnose COVID-19 by detecting a particular sequence from SARS-CoV-2. Such so-called singleplex methods give reliable results because they are”calibrated” to a single biomarker. However, determining whether a patient is infected with a new SARS-CoV-2 version or …
Novel technique gives quicker and more exact diagnostics in histopathology Kumar Jeetendra | May 1, 2021 Histology is the study of biological cells at a microscopic level. Also called microscopic anatomy, histology is widely used to offer identification of cancer and other diseases. For instance, tissue samples obtained during surgery might help to ascertain whether additional surgical action is needed, and additional surgery may be avoided if a diagnosis can be …
Antiviral T cells protected, viable as off-the-shelf treatment for painful complication stem cells Kumar Jeetendra | May 2, 2021 Infusion of T cells targeting BKV resulted in rapid responses, with 67.7% of patients seeing a complete or partial improvement in symptoms after 14 days. This increased to 81.6% of patients after 28 days post-infusion. No cases of grade 3 or grade 4 graft versus host disease (GVHD) or other infusion-related toxicities occurred. Addressing a …
Researchers examine signal necrotic cells that prompt phagocytic cells to overwhelm the dying cell Kumar Jeetendra | May 8, 2021 As people keep their homes clean and clutter in check, a crew of cells within the body is in charge of clearing the waste that the body generates, including cells that are dying. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means’eating cells’ “Phagocytosis is quite important for the body’s …
