Study recognizes biomarker gene mark that demonstrates likely liver toxicity Kumar Jeetendra | December 19, 2020 When agrochemical and pharmaceutical companies develop new products, they must test extensively for potential toxicity before obtaining regulatory approval. This testing usually involves lengthy and expensive animal research. A research team at University of Illinois has developed a gene biomarker identification technique that cuts the testing process down to a couple of days while still …
Hematoxylin compounds can specifically kill CALR freak disease cells Kumar Jeetendra | December 20, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
Digital chest drainage systems could help reduce COVID-19 spread, research show Kumar Jeetendra | December 20, 2020 Pioneering research, which reveals digital chest drains generate and disperse less aerosol generated particles in comparison to traditional water seal systems, has been published in the Seminars in Thoracic and Cardiovascular Surgery journal. The research was led by a group of thoracic consultants from Guy’s and St Thomas’ NHS Foundation Trust — home to one …
New comprehension of physical properties of chromatin may show how genome is encoded and decoded Kumar Jeetendra | December 21, 2020 University of Alberta researchers have found an answer to a basic question in genomic biology that has eluded scientists because the discovery of DNA: Over the nucleus of our cells, is the complex package of DNA and proteins called chromatin a solid or a liquid? Previously, fields like biochemistry operated under the premise that chromatin …
New drug mixture improves blood glucose manipulate and weight reduction in mice Kumar Jeetendra | December 23, 2020 Scientists have demonstrated that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published today in eLife. The results pave the way for clinical trials of this new drug combination as a more successful long-term remedy for countless individuals with …
Researchers pick out new weapon to war the growing tide of antibiotic-resistant bacteria Kumar Jeetendra | December 24, 2020 As scientists around the globe wage war against a publication, deadly virus, one University of Colorado Boulder laboratory is working on new weapons to battle a distinct microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unattended, could kill an estimated 10 million people annually by 2050. In a paper published Friday in …
Study famous how ecDNA fragments pressure gene amplification to generate drug resistance in cancer Kumar Jeetendra | December 26, 2020 Researchers headed by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the puzzle of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to create drug resistance in cancer. The study, published on December 23 in the journal Nature, provides new …
Researchers find out how shattered chromosomes make most cancers cells greater aggressive Kumar Jeetendra | December 27, 2020 Cancer is one of the world’s biggest health afflictions because, unlike some diseases, it’s a moving target, constantly evolving to evade and resist treatment. In a paper published in the December 23, 2020 online dilemma of Nature, researchers at University of California San Diego School of Medicine and the UC San Diego branch of the …
Surgery may expand length of endurance for metastatic breast malignant growth patients Kumar Jeetendra | December 28, 2020 They studied nearly 13,000 stage four breast cancer patients and found that those who had surgery as well as their other remedies had a survival advantage over those who had other therapies alone. Stage four breast cancer accounts for 6% of newly-diagnosed breast cancer cases. Systemic treatment, which may include treatments like chemotherapy, hormone therapies …
New UCLA-formed gadget moves mitochondria into at least 100,000 or more beneficiary cells Kumar Jeetendra | January 1, 2021 Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput way of transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders. A study, published …
Biomarkers can foresee how hereditarily identical cells act distinctively under pressure Kumar Jeetendra | January 10, 2021 A set of biomarkers not traditionally associated with cell fate can accurately forecast how genetically identical cells behave differently under pressure, according to a UT Southwestern study. The findings, published by Cell Reports as a Dec. 1 cover story, could eventually result in more predictable responses to pharmaceutical remedies. Groups of the same types of …
The Cancer Microbiome Atlas gives more clear picture of microbiota living in organs Kumar Jeetendra | January 14, 2021 Biomedical engineers at Duke University have devised an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). With a clearer picture of the microbiota living in a variety of organs in both healthy and cancerous states, researchers will now have the ability to find new biomarkers of disease and better understand …
