Compact, High Resolution Chromatography Flowmeter Kumar Jeetendra | October 9, 2020 TESTA Analytical Solutions e.K. has developed a new flowmeter which enables continuous measurement of flow rate without interference in chromatography systems. Flow rate is one of the most important parameters in any liquid chromatography system, it determines retention time or volume and has by nature a major influence on reproducibility. Compatible with all HPLC and …
New initiative identifies key parameters Inherent effective anti-tumor immunity Kumar Jeetendra | October 10, 2020 Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies. Targeting the”right” neoantigens – at a cancer vaccine or a cell treatment – has the promise to eliminate a patient’s cancer with minimal side effects. But countless mutations can exist in …
Bharat Biotech requested to submit total phase 2 information of its COVID-19 antibody before ph 3 preliminary Kumar Jeetendra | October 10, 2020 According to officials, the Hyderabad-based vaccine manufacturer applied to the Drugs Controller General of India (DCGI) on October 2, seeking its permission to run phase-3 randomised double-blind placebo-controlled multicentre trial of its COVID-19 vaccine candidate. The firm in its program said that the study would cover 28,500 subjects aged 18 years and above and would …
INTEGRA’s VOYAGER adjustable tip spacing electronic pipette: Increase workflow efficiency Kumar Jeetendra | October 10, 2020 Korcan Ayata is a member of the gastroenterology group – led by Prof. Dr Jan Niess – which focuses on researching mucosal immunology and gastroenterology. The group is interested in the role of immune cells in inflammatory conditions, studying how monocytes enter the tissue and differentiate into macrophages to have pro- or anti-inflammatory effects during …
High-dosage favipiravir ‘strong’ against COVID-19, HCQ totally incapable: Study Kumar Jeetendra | October 11, 2020 Research conducted at the KU Leuven Rega Institute in Belgium has found that the antimalarial drug hydroxychloroquine (HCQ) doesn’t limit the multiplication of the novel coronavirus. However, a very high dose of the flu drug favipiravir does have antiviral efficacy, according to their results. The researchers gave the hamsters either hydroxychloroquine or favipiravir for four …
Study uncovers significant antagonistic results in patients hospitalized with COVID-19 Kumar Jeetendra | October 11, 2020 While older age is widely known as a risk factor for increased morbidity and mortality due to COVID-19, younger patients have received less attention as a population vulnerable to adverse clinical outcomes. Researchers from Brigham and Women’s Hospital analyzed records from 419 hospitals utilizing the Premier Healthcare Database to examine the clinical trajectories of 3,222 …
Chemists propose another domino response to deliver organic compound against cancers Kumar Jeetendra | October 12, 2020 A group of chemists in RUDN University suggested a new response to produce organic compounds in 1 vessel. The end products proven to be effective against the cells of carcinomas, including drug-resistant ones. The new reaction was explained from the Bioorganic Chemistry journal. For many organic substances synthesis is a multistage process of step-by-step molecule …
Avenue Therapeutics gets letter from USFDA for intravenous tramadol Kumar Jeetendra | October 12, 2020 Therapeutics Inc has received a complete response letter (CRL) in the US health regulator for its new drug application for intravenous tramadol. The CRL in the US Food and Drug Administration (USFDA) has said that the regulator has decided it cannot approve the application for IV tramadol in its current form, Avenue Therapeutics said in …
Robust YMC-Triart C18 columns are the ideal decision for reliable and reproducible (U)HPLC examinations of peptides and oligonucleotides Kumar Jeetendra | October 12, 2020 Robust YMC-Triart C18 columns are the perfect choice for reliable and reproducible (U)HPLC analyses of peptides and oligonucleotides with exceptional resolution. The wide temperature- (up to 90°C) and pH-range (1-12) provide increased flexibility. Full MS compatibility is guaranteed due to virtually no column bleeding. Optionally available metal-free bioinert hardware inhibits unwanted interactions and ensures highly …
Age may not add to COVID-19 contamination risk: Study Kumar Jeetendra | October 13, 2020 The age of a person may not decide how likely they are infected by SARS-CoV-2, which induces COVID-19, according to a study which found that growth of symptoms, severity of the disease, and mortality are age-dependent. It’s been shown that elderly individuals disproportionately develop acute symptoms of COVID-19 and show higher mortality. Scientists, including those …
Pfizer changes convention for virus vaccine: study Kumar Jeetendra | October 13, 2020 Drugmaker Pfizer has modified the protocol for its late-stage study of its vaccine against the new coronavirus, this time to include more young participants. The company said on Monday that it’s received permission from the Food and Drug Administration to include adolescents aged 12 through 15 in its global COVID-19 vaccine study. New York-based Pfizer …
Johnson and Johnson stops preliminaries because of unexplained ailment in member Kumar Jeetendra | October 13, 2020 Johnson & Johnson said on October 12 it has temporarily paused clinical trials of its own COVID-19 vaccine candidate because of an unexplained illness in a research participant. In a statement, the company said that the participant’s illness has been reviewed and assessed by an independent data and safety monitoring board, and its clinical and …