Amniotic liquid undifferentiated cells may prompt better treatment for ischemic stroke Kumar Jeetendra | October 7, 2020 A study published today in STEM CELLS Translational Medicine points the way to a potential new avenue of treatment for ischemic stroke. The study, led by Annamaria Cimini, Ph.D., of the University of L’Aquila, and Liborio Stuppia, M.D., of D’Annunzio University, Italy, shows how the secretome of amniotic fluid stem cells can restore neuronal plasticity …
New initiative identifies key parameters Inherent effective anti-tumor immunity Kumar Jeetendra | October 10, 2020 Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies. Targeting the”right” neoantigens – at a cancer vaccine or a cell treatment – has the promise to eliminate a patient’s cancer with minimal side effects. But countless mutations can exist in …
Study uncovers significant antagonistic results in patients hospitalized with COVID-19 Kumar Jeetendra | October 11, 2020 While older age is widely known as a risk factor for increased morbidity and mortality due to COVID-19, younger patients have received less attention as a population vulnerable to adverse clinical outcomes. Researchers from Brigham and Women’s Hospital analyzed records from 419 hospitals utilizing the Premier Healthcare Database to examine the clinical trajectories of 3,222 …
Female mosquitoes can distinguish a mix of four unique substances in blood Kumar Jeetendra | October 13, 2020 Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Researchers are learning what people taste like to mosquitoesdown to the individual neurons that sense blood’s distinctive, flavorful taste. Female mosquitoes have a sense of taste that is especially tuned to detect a combination of …
Study gives conceivable clarification to reformist course of different sclerosis in mice Kumar Jeetendra | October 17, 2020 People with multiple sclerosis (MS) gradually develop increasing functional impairment. Researchers at Karolinska Institutet in Sweden have found a possible explanation for the progressive course of this disease in mice and how it can be reversed. The analysis, which is published in Science Immunology, can prove beneficial to future treatments. MS is a chronic inflammatory …
Trial ALS drug shows potential to drag out patient endurance Kumar Jeetendra | October 18, 2020 An experimental medicine that was recently shown to slow the progression of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, has now demonstrated the capacity to also prolong patient survival. The findings come from a clinical trial conducted by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts …
CBD could lessen lung harm brought about by COVID-19 Kumar Jeetendra | October 19, 2020 One way CBD appears to reduce the”cytokine storm” that damages the lungs and kills many individuals with COVID-19 is by enabling an increase in levels of a natural peptide called apelin, which is proven to reduce inflammation and whose levels are dramatically reduced in the face of this storm. Dental College of Georgia and Medical …
Researchers propose that antimalarial medications could be repurposed to treat COVID-19 Kumar Jeetendra | October 20, 2020 An international group of researchers believe there is enough evidence that anti-malarial drugs could be repurposed to treat COVID-19 and they need to be evaluated for efficacy in clinical trials. The review article, published online in Trends in Parasitology, summarizes the evidence for its antiviral and anti-inflammatory properties of particular anti-malarial drugs which could play …
Oral bacteria persevere on squandered biting gums for quite a long time Kumar Jeetendra | October 24, 2020 Researchers from the Institute of Integrative Systems Biology (I2SysBio), a joint centre of the University of Valencia and the CSIC, have examined the bacteria from used chewing gums from five different states. The research, just published in the journal Scientific Reports, shows that the bacterial load of gum changes in a matter of weeks and …
Antenatal steroids improve preterm infant endurance in low-asset settings, discovers study Kumar Jeetendra | October 24, 2020 The results of a new clinical trial, published today in the New England Journal of Medicine, show that dexamethasone- a glucocorticoid used to treat many conditions, including rheumatic problems and severe COVID-19- may boost survival of premature babies when given to pregnant women at risk of premature birth in low-resource settings. The WHO ACTION-I trial …
Myeloid cells can smother insusceptible reaction, advance cerebrum metastasis Kumar Jeetendra | October 28, 2020 Scientists have long thought that the brain protects itself from an aggressive immune response to keep inflammation down. However, that evolutionary management may work against it when a cancer cell tries to spread to the brain, researchers at the University of Notre Dame have found. In recently published research in the journal Cell, researchers showed …
Drug used to control pulse may improve malignant growth patients’ reaction to immunotherapy Kumar Jeetendra | November 1, 2020 The exact same biochemical triggers which spur a”flight or fight” reaction once we encounter threats may help tumor cells to thrive. A group of researchers from Roswell Park Comprehensive Cancer Center is looking at ways to interrupt that dynamic so that cancer therapies can be effective. Their latest work, published today in Clinical Cancer Research, …