The Cancer Microbiome Atlas gives more clear picture of microbiota living in organs Kumar Jeetendra | January 14, 2021 Biomedical engineers at Duke University have devised an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). With a clearer picture of the microbiota living in a variety of organs in both healthy and cancerous states, researchers will now have the ability to find new biomarkers of disease and better understand …
Analysts build up a little, yet successful technique for forestalling premature birth Kumar Jeetendra | January 14, 2021 In a study in mice and human cells, Johns Hopkins Medicine researchers say that they have developed a little, yet effective method for preventing premature birth. The vaginally-delivered treatment contains nanosized (billionth of a meter) particles of drugs that easily penetrate the vaginal wall to reach the uterine muscles and keep them from contracting. If …
Recently recognized supplement helps the gut review earlier diseases and execute attacking bacteria Kumar Jeetendra | January 17, 2021 Scientists studying the body’s natural defenses against bacterial disease have identified a nutritional supplement –taurine–that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn). The finding, published in the journal Cell by scientists from five institutes of the National Institutes of Health, could help efforts seeking alternatives to antibiotics. …
Bacteria responsible for seafood related stomach disturbs can go torpid and “wake up” Kumar Jeetendra | January 20, 2021 Vibrio parahaemolyticus is a marine bacterium that can lead to gastroenteritis in humans when eaten in raw or undercooked shellfish such as oysters and mussels. Some of these bacteria have the ability to turn dormant in poor growth conditions such as cold temperatures – and can stay in that state of hibernation for long periods …
Scientists find uncommon hereditary disorder that influences the brain, heart and facial highlights Kumar Jeetendra | January 21, 2021 Researchers at the National Institutes of Health have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart and facial features. Named linkage-specific-deubiquitylation-deficiency-induced embryonic defects syndrome (LINKED), it is caused by a mutated version of the OTUD5 gene, which interferes with key molecular actions in embryo development. The findings indicate …
Corning to feature most current product in 3D cell culture portfolio at SLAS2021 Kumar Jeetendra | January 23, 2021 Corning Incorporated will highlight its hottest technologies that support the advancement of 3D cell culture, automation, and drug discovery in this year’s virtual Society for Laboratory Automation and Screening (SLAS) seminar on Jan. 25 through 27. Now more than ever, tools used to ease scale-up, reproducibility, and consistency of 3D cell culture are helping empower …
Pancreatic β cell-inferred exosomal miR-29s control glucose homeostasis Kumar Jeetendra | January 24, 2021 In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang’s team at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig’s group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in reaction to high levels of free fatty acids (FFAs). Formerly, Chen-Yu Zhang’s team identified …
UC research group utilizes zebrafish to contemplate a quality change that causes intrinsic scoliosis Kumar Jeetendra | January 24, 2021 Popular in aquariums throughout the world, the zebrafish is native to South Asia. But here in a Cincinnati Children’s laboratory, the freshwater variant plays a vital role in scientific discovery. The patterning of the zebrafish’s spine gives the appearance of stripes; it is controlled by segmentation genes which function as a clock. Zinani is part …
Second-generation double antibody shields from SARS-CoV-2 and its tried variations Kumar Jeetendra | January 25, 2021 Additionally, it prevents the virus from mutating to resist the treatment . Antibody-based immunotherapy was already proven to work against COVID-19 but faces two chief obstacles: it requires to work against the circulating viral variants; it has to avoid formation of new variants, that can rapidly ensue using a mechanism similar to that leading to …
UNSW builds up a clay based ink to 3D-print bone parts with living cells Kumar Jeetendra | January 26, 2021 3D printers may one day become a permanent fixture of the operating theatre after UNSW scientists showed they could print bone-like structures comprising living cells. Researchers from UNSW Sydney have developed a ceramic-based ink which may allow surgeons in the long run to 3D-print bone elements complete with living cells which could be used to …
Substances in tick spit actuate insusceptible reaction smothering proteins in cattles Kumar Jeetendra | January 28, 2021 Scientists from Hokkaido University, Japan and Universidade Federal do Rio Grande do Sul and Universidade Federal do Rio de Janeiro, Brazil, have revealed that substances in tick saliva trigger immune response-suppressing proteins in cows that facilitates the transmission of tick-borne diseases. The finding was published in the journal Scientific Reports and could assist in the …
New gene based vaccine procedure gets award from the Bill and Melinda Gates Foundation Kumar Jeetendra | January 29, 2021 The AAVCOVID vaccine application, a novel gene-based vaccine plan that utilizes an adeno-associated virus (AAV) vector, was granted an award for up to $2.1 million from the Bill & Melinda Gates Foundation. The grant will assist the effort to bring further preclinical validation into the AAV vaccine platform. An AAVCOVID vaccine candidate is set to …
