Hematoxylin compounds can specifically kill CALR freak disease cells Kumar Jeetendra | December 20, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
New comprehension of physical properties of chromatin may show how genome is encoded and decoded Kumar Jeetendra | December 21, 2020 University of Alberta researchers have found an answer to a basic question in genomic biology that has eluded scientists because the discovery of DNA: Over the nucleus of our cells, is the complex package of DNA and proteins called chromatin a solid or a liquid? Previously, fields like biochemistry operated under the premise that chromatin …
Researchers find out protein that adjusts gene interest to healthy nutrient stages in roundworms Kumar Jeetendra | December 23, 2020 Changing a fertilized egg into a fully functional adult is a complicated endeavor. Cells must split, move, and mature at specific times. Developmental genes control that process, turning on and off at a choreographed way. However, the environment affects development. They discovered a master switch developing worms use to pause growth when nutrients are scarce. …
Researchers pick out new weapon to war the growing tide of antibiotic-resistant bacteria Kumar Jeetendra | December 24, 2020 As scientists around the globe wage war against a publication, deadly virus, one University of Colorado Boulder laboratory is working on new weapons to battle a distinct microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unattended, could kill an estimated 10 million people annually by 2050. In a paper published Friday in …
Polygenic threat ratings from multi-populace information should enhance IBD predictions Kumar Jeetendra | December 25, 2020 Using genetic data from nearly 30,000 individuals, Mount Sinai researchers have assembled hazard scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn’s disease and ulcerative colitis. The research was published in Gastroenterology on December 24. The researchers found that polygenic risk scores, …
Scientists grow new framework for direct location of SARS-CoV-2 in aerosols Kumar Jeetendra | December 28, 2020 Researchers in the Polytechnic University of Valencia (UPV), in collaboration with specialists from the University of Valencia (UV), have produced a new system based on a high-sensitivity mass biosensor that continuously monitors signals for the immediate detection of SARS-CoV-2 in environmental aerosols. The device, in prototype stage, makes it possible to appraise the quality of …
New UCLA-formed gadget moves mitochondria into at least 100,000 or more beneficiary cells Kumar Jeetendra | January 1, 2021 Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput way of transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders. A study, published …
FDA-endorsed COVID-19 medication should be utilized warily, says UC researcher Kumar Jeetendra | January 4, 2021 While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics continue to be necessary to treat hepatitis patients. One of these treatments, remdesivir, is the first and only antiviral agent of its type the U.S. Food and Drug Administration (FDA) has approved so far for COVID-19. Research at the University …
Scientists disentangle the cycle that makes virus irresistible Kumar Jeetendra | January 9, 2021 Researchers have for the first time identified how viruses like the poliovirus and the common cold virus’package up’ their genetic code, allowing them to infect cells. The findings, published today (Friday, 8 January) in the journal PLOS Pathogens by a team from the Universities of Leeds and York, open up the possibility that medication or …
FDA cautions medical services suppliers and clinical lab staff about SARS-CoV-2 viral transformation Kumar Jeetendra | January 10, 2021 The U.S. Food and Drug Administration is alerting clinical laboratory staff and health care providers that the FDA is monitoring the potential effect of viral mutations, including an emerging version from the United Kingdom known as the B.1.1.7 variant, on approved SARS-CoV-2 molecular tests, which false negative results can occur with almost any molecular test …
Scientists gives better comprehension of how antibiotic resistance emerges Kumar Jeetendra | January 11, 2021 Researchers at the Quadram Institute on the Norwich Research Park have shown how the development of antibiotic resistance by bacteria may have’side-effects’ for them including affecting their ability to induce disease. Antibiotic resistance is still one of the best challenges to global health with very few new antibiotics and widespread immunity. It’s been estimated that …
New fluorescence microscopy strategy produces nanoscale 3D pictures of living cells Kumar Jeetendra | January 12, 2021 A new fluorescence microscopy technique has produced the world’s first nanoscale 3D images of molecules in a whole, living cell, researchers at KTH Royal Institute of Technology reported. Ilaria Testa, an associate professor at KTH and researcher at the Science for Life Laboratory, says the technique is capable of generating images with precision that until …
