Researchers enlighten how a few antibodies can viably disable ebolaviruses Kumar Jeetendra | April 18, 2021 Some survivors of ebolavirus outbreaks create antibodies that may broadly neutralize those viruses–and today , scientists at Scripps Research have illuminated how these antibodies can disable the viruses so efficiently. The insights might be helpful for developing effective treatments. Ebolavirus is a family of often-deadly viruses that includes Ebola virus and lots of lesser-known viruses …
FDA denies EUA for monoclonal antibody treatment bamlanivimab to treat patients with COVID Kumar Jeetendra | April 18, 2021 Now, the U.S. Food and Drug Administration revoked the emergency use authorization (EUA) that allowed for the investigational monoclonal antibody treatment bamlanivimab, when administered alone, to be utilized for treating mild-to-moderate COVID-19 in adults and certain pediatric patients. Based on its ongoing analysis of emerging scientific data, specifically the sustained increase of SARS-CoV-2 viral variants …
Basic dietary enhancement enhances schizophrenic traits in mice Kumar Jeetendra | April 20, 2021 After additional experiments, including visualizing the fluorescently stained dancing advantage of brain cells, researchers concluded that the nutritional supplement likely protects proteins which build neurons’ mobile skeletons. The supplement betaine was initially isolated from sugar beets and is often associated with sweetness or umami flavor. Healthy levels of betaine come from both outside food sources …
New hereditarily encoded sensor recognizes drugs of abuse Kumar Jeetendra | April 29, 2021 A genetically encoded sensor to detect hallucinogenic compounds has been developed by researchers at the University of California, Davis. Named psychLight, the sensor could be used in discovering new treatments for mental illness, in neuroscience research and to detect drugs of abuse. The work is published April 28 in the journal Cell. Compounds associated with …
Antiviral T cells protected, viable as off-the-shelf treatment for painful complication stem cells Kumar Jeetendra | May 2, 2021 Infusion of T cells targeting BKV resulted in rapid responses, with 67.7% of patients seeing a complete or partial improvement in symptoms after 14 days. This increased to 81.6% of patients after 28 days post-infusion. No cases of grade 3 or grade 4 graft versus host disease (GVHD) or other infusion-related toxicities occurred. Addressing a …
A solitary archaeal compound can create a spectacular scope of regular and non-common cardiolipins Kumar Jeetendra | May 7, 2021 Cells of all life forms are surrounded by a membrane that’s made of phospholipids. One of them are the cardiolipins, which form another class due to their distinctive structure. When studying the enzyme that’s responsible for generating cardiolipins in archaea (single-cell organisms that constitute a separate domain of life), biochemists at the University of Groningen …
New COVID-19 testing innovation is a less expensive, quicker choice to tube-based RT-PCR tests Kumar Jeetendra | May 18, 2021 Throughout the COVID-19 pandemic, supply chain shortages of reagents and test kits have restricted the rapid expansion of clinical testing required to contain the virus. Its accuracy was 100 percent predictive in clinical trials, researchers explain in The Journal of Molecular Diagnostics, published by Elsevier. Sensitivity is critical for early detection of COVID-19 infection where …
New medication like compound could adequately hinder a critical step in malaria parasite life cycle Kumar Jeetendra | May 19, 2021 Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a vital step in the malaria parasite life cycle and are working to develop this compound into a potential first of its type malaria treatment. While drugs and mosquito control have reduced levels of …
Growing genomic research into different ancestries yields more and better outcomes Kumar Jeetendra | June 1, 2021 Currently published in Nature Genetics, their findings demonstrate that expanding research into different ancestries yields more and better results, in addition to ultimately benefitting global patient care. Up to now nearly 87 percent of genomic research of the type was conducted in Europeans. The global study team examined data across a wide assortment of cohorts, …
3Brain AG CorePlate™ technology combines microchips and AI in a revolutionary new approach to drug discovery Kumar Jeetendra | June 8, 2021 Wädenswil, Greater Zurich Area, Switzerland, June 8, 2021 – – 3Brain AG has announced a new technology based on a unique combination of microchips and AI that promises to change the way drug candidates are selected at the preclinical level to enter into clinical trials – and to maximize their chances of success. Using CorePlate™ …
Ladies treated with fertility drugs don’t have expanded breast cancer risk, study shows Kumar Jeetendra | June 21, 2021 Drugs frequently used during fertility treatments to release eggs don’t increase the chance of developing breast cancer, new research has shown. Researchers from King’s College London, in partnership with King’s Fertility, analyzed studies between 1.8 million women undergoing fertility treatments. These women were followed up in studies for a normal period of 27 years and …
Study uncovers the complex cell mechanism of Ebola Kumar Jeetendra | July 8, 2021 Mount Sinai researchers discovered the intricate cellular mechanisms of Ebola virus. This could help to explain the severe effects on people and provide potential treatment or prevention. The team published a study in mBio that showed how VP24, a protein from the Ebola virus interacts with the double-layered cell membrane (known as the nucleus) and …
