New device empowers study of SARS-CoV-2 mutant range by ultrasequencing Kumar Jeetendra | February 15, 2021 SARS-CoV-2 genome is three times larger than flu genome. Both consist of NRA molecules which mutate when replicate. It is essential to know its mutant spectrum, in other words, its”fingerprints”, to achieve an appropriate treatment that reduces its infectivity -the capacity of pathogens to invade organisms and cause infections-, since its composition of variables could …
Immunomodulatory drugs improve the achievement pace of cancer therapy Kumar Jeetendra | February 15, 2021 Immunomodulatory drugs, for example, Contergan derivatives lenalidomide and pomalidomide, have significantly improved the treatment of hematologic malignancies such as multiple myeloma. Researchers at the Technical University of Munich (TUM) have now further decoded the mode of action within this class of drugs. At exactly the exact same time, they identified new revolutionary targeted cancer therapies. …
An upgraded interaction to detach and cleanse magnetic nanoparticles Kumar Jeetendra | February 20, 2021 Magnetic nanoparticles biosynthesized by germs might soon play an significant role in biomedicine and biotechnology. Researchers at the University of Bayreuth have developed and optimized a procedure for the purification and isolation of the particles from bacterial cells. In initial tests, magnetosomes showed good biocompatibility when compared with human cell lines. The results presented in …
Genomic Data Commons offers the biggest asset in cancer genomics Kumar Jeetendra | February 27, 2021 The National Cancer Institute’s Genomic Data Commons (GDC), launched in 2016 by then-Vice President Joseph Biden and hosted at the University of Chicago, has become one of the largest and most widely used resources in cancer genomics, with over 3.3 petabytes of data from more than 65 jobs and more than 84,000 anonymized patient cases, …
Genomic surveillance can help recognize how SARS-CoV-2 spreads in care homes Kumar Jeetendra | March 4, 2021 Care homes are at high risk of experiencing outbreaks of COVID-19, the disease brought on by SARS-CoV-2. Older people and people affected by heart disease, respiratory disease and type 2 diabetes – all of which increase with age – are at greatest risk of severe disease and even death, which makes the care home population …
Killing antibodies actuated by COVID-19 vaccines less successful against new variants Kumar Jeetendra | March 15, 2021 SARS-CoV-2, the virus that causes COVID-19, has mutated through the pandemic. New variants of this virus have arisen around the world, including variants that might possess increased capacity to spread or evade the immune system. Such variations have been identified in California, Denmark, the U.K., South Africa and Brazil/Japan. Recognizing how well the COVID-19 vaccines …
Study offers understanding into metabolic pathways hijacked by SARS-CoV-2 for viral replication Kumar Jeetendra | March 16, 2021 When SARS-CoV-2, the virus which causes COVID-19, infects a human cell, it quickly begins to replicate by seizing the cell’s existing metabolic machinery. The infected cells churn out thousands of viral genomes and proteins while halting the creation of their own sources. Researchers from Brigham and Women’s Hospital, Massachusetts General Hospital (MGH), and the Broad …
Scientists portray regions of DNA that sway MECP2 expression Kumar Jeetendra | March 19, 2021 Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans. These findings, published in Genes & Development, are helping to shed light on the purpose of …
Secret genetic defects can prompt a wide range of serious illnesses Kumar Jeetendra | March 20, 2021 For the first time researchers from Hebrew University of Jerusalem, Radboudumc, Maastricht UMC+ and worldwide colleagues have gained insight to the”hidden genetic defects” of the general European population. This is important as these defects, if inherited from the father and mother, can result in all kinds of disorders in their children. Research in the Dutch …
FDA approves first AI based COVID-19 non-diagnostic screening Kumar Jeetendra | March 21, 2021 Now, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the first machine learning-based Coronavirus Disease 2019 (COVID-19) non-diagnostic testing apparatus that identifies certain biomarkers that are indicative of some kinds of conditions, such as hypercoagulation (a condition causing blood to clot more readily than normal). The Tiger Tech COVID Plus …
Study offers a non-obtrusive avenue for monitoring buildings for COVID-19 Kumar Jeetendra | April 14, 2021 A study done in rooms where COVID-19 patients were isolated reveals that the virus’s RNA – part of the genetic material inside a virus – can persist up to a month in dust. The study did not evaluate whether dust may transmit the virus to people. It could, however, offer another option for monitoring COVID-19 …
Pregnancy builds the danger of first-time symptomatic kidney stone Kumar Jeetendra | April 15, 2021 Though researchers have long known that several physiological and anatomical changes occur during pregnancy which could contribute to kidney stone formation, evidence of the connection has been lacking. An observational study that reviewed the medical records for nearly 3,000 female patients from 1984 to 2012 finds that pregnancy increases the risk of a first-time symptomatic …
