Conceivable new anti-microbial created for drug-resistant pulmonary microorganism Kumar Jeetendra | December 9, 2020 Scientists from Johns Hopkins University and Medicine have developed a potential new antibiotic for a pathogen that is notoriously resistant to drugs and often lethal for people with cystic fibrosis and other lung disorders. The pathogen, called Mycobacterium abscessus, is related to some better-known bacterium that causes tuberculosis and leprosy but has recently emerged as …
Colon lining discharges hydrogen peroxide to shield the body from gut microorganisms Kumar Jeetendra | December 10, 2020 Scientists at UC Davis Health have discovered that an enzyme in the colon lining releases hydrogen peroxide (H2O2) – a known disinfecting chemical – to protect the body from gut microbes. Their study, published Dec. 9 in the journal Cell Host and Microbe, sheds light on the way microorganisms are spatially organized in the colon. …
Hematoxylin compounds can specifically kill CALR mutant cancer cells Kumar Jeetendra | December 11, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Researchers of the research team of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
Active enzymes are expected to open full advantages of Vitamin A in carrots Kumar Jeetendra | December 14, 2020 Carrots are a good source of beta-carotene, which is a precursor of vitamin A. But to get the full health benefits of this superfood, you want an active enzyme to produce this vitamin. Studies with mice and humans reveal the conversion of beta-carotene to vitamin A reduces”bad” cholesterol in the blood. Therefore, beta-carotene can help …
Hematoxylin compounds can specifically kill CALR freak disease cells Kumar Jeetendra | December 20, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
Researchers pick out new weapon to war the growing tide of antibiotic-resistant bacteria Kumar Jeetendra | December 24, 2020 As scientists around the globe wage war against a publication, deadly virus, one University of Colorado Boulder laboratory is working on new weapons to battle a distinct microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unattended, could kill an estimated 10 million people annually by 2050. In a paper published Friday in …
Poisonous pesticide transformed into treatment against antibiotic-resistant bacteria Kumar Jeetendra | December 30, 2020 They are used as pesticides and fungicides. However, these substances could be poisonous to humans and cause mutations. As they aren’t frequently used, there’s little data about them in the medicinal chemistry literature. However, it has been suggested recently that the groups of substances that are traditionally avoided can help to fight pathogenic bacteria. Yet, …
Analysts build up a little, yet successful technique for forestalling premature birth Kumar Jeetendra | January 14, 2021 In a study in mice and human cells, Johns Hopkins Medicine researchers say that they have developed a little, yet effective method for preventing premature birth. The vaginally-delivered treatment contains nanosized (billionth of a meter) particles of drugs that easily penetrate the vaginal wall to reach the uterine muscles and keep them from contracting. If …
World’s first completely reversible control of the circadian clock Kumar Jeetendra | January 26, 2021 The Nagoya University Institute of Transformative Bio-Molecules (WPI-ITbM) research team of Designated Associate Professor Tsuyoshi Hirota, Postdoctoral Fellow Simon Miller, Professor Kenichiro Itami and grad student Tsuyoshi Oshima (Research Fellowship for Young Scientists, JSPS), in collaboration with the team of Professor Ben Feringa and Postdoctoral Fellow Dušan Kolarski of Groningen University in the Netherlands, have …
Substances in tick spit actuate insusceptible reaction smothering proteins in cattles Kumar Jeetendra | January 28, 2021 Scientists from Hokkaido University, Japan and Universidade Federal do Rio Grande do Sul and Universidade Federal do Rio de Janeiro, Brazil, have revealed that substances in tick saliva trigger immune response-suppressing proteins in cows that facilitates the transmission of tick-borne diseases. The finding was published in the journal Scientific Reports and could assist in the …
Hamilton BiOS® Automated Sample Storage System Selected for New Health Sciences Research Building (HSRB)- II at Emory University Kumar Jeetendra | February 9, 2021 Hamilton Storage is very happy to confirm that the Hamilton BiOS® automatic storage system will be installed as part of a shared biorepository for preserving biological material at Emory University’s new Woodruff Health Sciences Center Health Sciences Research Building (HSRB)-II. This state-of-the-art biomedical research facility construction, including installation of the BiOS, is expected to be …
Drug-discovery collaboration discovers potential new antimalarial drug candidates Kumar Jeetendra | April 23, 2021 Potential new antimalarial drug candidates are being developed through an protracted drug-discovery collaboration between Australian medical research institute WEHI and Janssen Pharmaceutica NV. The collaboration was facilitated by Johnson & Johnson Innovation. A collaborative research team discovered compounds with antimalarial activity within a collection of 80,000 drug-like molecules at the Janssen Jump-stARter Compound Library, a …
