Avenue Therapeutics gets letter from USFDA for intravenous tramadol Kumar Jeetendra | October 12, 2020 Therapeutics Inc has received a complete response letter (CRL) in the US health regulator for its new drug application for intravenous tramadol. The CRL in the US Food and Drug Administration (USFDA) has said that the regulator has decided it cannot approve the application for IV tramadol in its current form, Avenue Therapeutics said in …
Chemists propose another domino response to deliver organic compound against cancers Kumar Jeetendra | October 12, 2020 A group of chemists in RUDN University suggested a new response to produce organic compounds in 1 vessel. The end products proven to be effective against the cells of carcinomas, including drug-resistant ones. The new reaction was explained from the Bioorganic Chemistry journal. For many organic substances synthesis is a multistage process of step-by-step molecule …
Study uncovers significant antagonistic results in patients hospitalized with COVID-19 Kumar Jeetendra | October 11, 2020 While older age is widely known as a risk factor for increased morbidity and mortality due to COVID-19, younger patients have received less attention as a population vulnerable to adverse clinical outcomes. Researchers from Brigham and Women’s Hospital analyzed records from 419 hospitals utilizing the Premier Healthcare Database to examine the clinical trajectories of 3,222 …
High-dosage favipiravir ‘strong’ against COVID-19, HCQ totally incapable: Study Kumar Jeetendra | October 11, 2020 Research conducted at the KU Leuven Rega Institute in Belgium has found that the antimalarial drug hydroxychloroquine (HCQ) doesn’t limit the multiplication of the novel coronavirus. However, a very high dose of the flu drug favipiravir does have antiviral efficacy, according to their results. The researchers gave the hamsters either hydroxychloroquine or favipiravir for four …
New initiative identifies key parameters Inherent effective anti-tumor immunity Kumar Jeetendra | October 10, 2020 Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies. Targeting the”right” neoantigens – at a cancer vaccine or a cell treatment – has the promise to eliminate a patient’s cancer with minimal side effects. But countless mutations can exist in …
Takeda-drove COVID-19 plasma treatment enters clinical preliminary with first patient Kumar Jeetendra | October 9, 2020 Japan’s Takeda Pharmaceutical Co said on Friday an alliance of drugmakers that it spearheads has enrolled its first patient in a global clinical trial of a blood plasma treatment for COVID-19 after months of regulatory delays. The phase 3 trial from the group, referred to as the CoVIg Plasma Alliance, intends to enroll 500 adult …
Researchers identify enduring antibodies in blood, spit tests from COVID-19 patients Kumar Jeetendra | October 9, 2020 Scientists, including among Indian-origin, have documented the persistence of antibodies that target the novel coronavirus from the blood and saliva of patients with COVID-19 at least three months after symptom onset, a finding that may lead to alternate methods of testing for the viral infection. The study, published in the journal Science, points to the …
China says will buy COVAX immunizations for 1% of populace Kumar Jeetendra | October 9, 2020 China will purchase COVID-19 vaccines for just 1 percent of its population, or 15 million people, via a global scheme backed by the World Health Organization, the Foreign Ministry said on Friday. Beijing’s move to join the COVAX programme means China”will be procuring vaccines through the facility for a percentage of their own population, just …
Indo-Israel fast COVID-19 testing examination to fructify in ‘matter of days’: Israeli agent Kumar Jeetendra | October 9, 2020 A game-changer rapid COVID-19 testing technologies being jointly developed by India and Israel should be prepared for rollout in”a matter of days” and it’ll have the ability to give test results in less than a minute by simply requiring an individual to blow into a tube, the Israeli envoy to India has stated. Ambassador Ron …
India decays proposition to test Russia’s COVID-19 immunization Sputnik-V in huge examination Kumar Jeetendra | October 8, 2020 India’s drug regulator has knocked back a proposal from Dr Reddy’s Laboratories Ltd to conduct a large study in the nation to evaluate Russia’s Sputnik-V COVID-19 vaccine and has asked it to test the vaccine in a smaller trial. The recommendations by an expert panel of the Central Drugs Standard Control Organisation (CDSCO) noted that …
Designers develop plant-based splash that could be utilized in N95 mask filters Kumar Jeetendra | October 7, 2020 Engineers have invented a way to spray extremely thin wires made of a plant-based material that might be used in N95 mask filters, devices that harvest energy for electricity, and potentially the production of human organs. The procedure involves spraying methylcellulose, a renewable plastic material derived from plant cellulose, on 3D-printed and other objects ranging …
Amniotic liquid undifferentiated cells may prompt better treatment for ischemic stroke Kumar Jeetendra | October 7, 2020 A study published today in STEM CELLS Translational Medicine points the way to a potential new avenue of treatment for ischemic stroke. The study, led by Annamaria Cimini, Ph.D., of the University of L’Aquila, and Liborio Stuppia, M.D., of D’Annunzio University, Italy, shows how the secretome of amniotic fluid stem cells can restore neuronal plasticity …
