Researchers locate mechanism underlying plasticity in grownup brains Kumar Jeetendra | December 27, 2020 Developing brains continuously sprout new neuronal connections called synapses as they understand and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while links deemed unnecessary are pruned away. Adult brains experience similar pruning, but it was unclear why or how synapses in …
Hyderabad set to turn out to be international hub for COVID-19 vaccine in 2021 Kumar Jeetendra | December 27, 2020 As the world is set to brace for a new year amid the COVID-19 pandemic, the city is poised to emerge as a’saviour’ from the killer virus, with as many as five vaccine manufacturing companies based in Hyderabad racing to bring out an antidote. The vaccine development process by Bharat Biotech, Biological E Ltd and …
Study famous how ecDNA fragments pressure gene amplification to generate drug resistance in cancer Kumar Jeetendra | December 26, 2020 Researchers headed by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the puzzle of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to create drug resistance in cancer. The study, published on December 23 in the journal Nature, provides new …
Russia approves Sputnik V COVID-19 vaccine for humans over 60: Report Kumar Jeetendra | December 26, 2020 Russia on Saturday approved its main COVID-19 vaccine, Sputnik V, for use by people over the age of 60, Russian news agencies cited the health ministry as saying. People over 60 have thus far been excluded from Russia’s national inoculation programme, as the shot was tested on this age group separately.
UK scientists trial immediate immunity antibody drug remedy for COVID-19 Kumar Jeetendra | December 26, 2020 Researchers in the UK have started trials of innovative antibody drug treatments that they hope could offer instant protection against COVID-19. The University College London Hospitals NHS Trust (UCLH) stated that the researchers at the Storm Chase study believe a Long Acting AntiBody (LAAB) known as AZD7442, developed by AstraZeneca, may provide immediate and long-term …
Oxford COVID-19 vaccine may also come to be the primary to get Indian regulator’s nod for emergency use Kumar Jeetendra | December 26, 2020 With preparations underway for a possible vaccine-rollout by January, the Indian drug regulator is considering the united kingdom, which sources consider may give its nod to the Oxford COVID-19 vaccine following week, before deciding on giving emergency use authorisation to the Serum Institute that’s manufacturing the shots . When the UK drug regulator gives its …
Polygenic threat ratings from multi-populace information should enhance IBD predictions Kumar Jeetendra | December 25, 2020 Using genetic data from nearly 30,000 individuals, Mount Sinai researchers have assembled hazard scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn’s disease and ulcerative colitis. The research was published in Gastroenterology on December 24. The researchers found that polygenic risk scores, …
Study clarifies the impact of getting old on hematopoietic stem cells Kumar Jeetendra | December 25, 2020 By shifting mouse elderly hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was shown that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem cells. On the other hand, the function of elderly HSCs failed to recover in the young bone marrow …
Researchers pick out new weapon to war the growing tide of antibiotic-resistant bacteria Kumar Jeetendra | December 24, 2020 As scientists around the globe wage war against a publication, deadly virus, one University of Colorado Boulder laboratory is working on new weapons to battle a distinct microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unattended, could kill an estimated 10 million people annually by 2050. In a paper published Friday in …
A short-reduce in photosynthetic equipment can permit needles of pine bushes to live green Kumar Jeetendra | December 24, 2020 How do conifers which are used for example as Christmas trees keep their green needles over the boreal winter when many trees drop their leaves? Science hasn’t provided a good response to this question but now an international group of scientists, including researchers in Umeå University, has deciphered that a short-cut in the photosynthetic machinery …
Serum Institute starts Phase I of experimental COVID-19 vaccine with Dynavax adjuvant Kumar Jeetendra | December 24, 2020 Serum Institute of India, the world’s largest vaccine manufacturer by volume and Nasdaq-listed biopharma company Dynavax Technologies Corporation stated they started dosing the initial participants as part of the Phase 1/2 clinical trial. An adjuvant is used to boost the efficacy of this vaccine. The Phase 1/2 clinical trial will assess the safety and immunogenicity …
Moderna expects its COVID-19 vaccine to shield towards UK coronavirus variant Kumar Jeetendra | December 24, 2020 Moderna Inc said it anticipates that the immunity induced by its COVID-19 vaccine would be protective against the coronavirus variants reported in britain. The company said it intends to conduct tests to confirm the vaccine’s action against any strain. Moderna’s comments came amid the British government’s plan to put massive swathes of England under its …
