Study shows how mast cells manage calcium levels to control the invulnerable reaction Kumar Jeetendra | July 23, 2020 Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune disorders and allergies. An Ludwig-Maximilian-Universitaet (LMU) in Munich group has dissected how mast cells modulate their calcium levels to maintain the immune response under control. The immune system defends us against attack by germs and viruses and also …
Analysts expect to recognize illness resistance instruments in sepsis patients Kumar Jeetendra | October 16, 2020 Sepsis is estimated to cause 11 million deaths each year in the world. Its treatment is based on the use of antibiotics and organ support measures, but many times it fails because of unsuccessful attempts at controlling the immune reaction. Surviving a serious infection requires the activation of mechanisms both of resistance. This reduce the …
Trial ALS drug shows potential to drag out patient endurance Kumar Jeetendra | October 18, 2020 An experimental medicine that was recently shown to slow the progression of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, has now demonstrated the capacity to also prolong patient survival. The findings come from a clinical trial conducted by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts …
Study uncovers new and basic subtleties of how photoreceptors work Kumar Jeetendra | October 26, 2020 Moving around in the half-light is difficult but not impossible. To help us in this undertaking we have the rods, a type of light-sensitive cells (photoreceptors) present in the retina of vertebrates, capable of detecting very low lights that allow to move about even in poorly lit cellars or caves. They are biological wonders capable …
New UCLA-formed gadget moves mitochondria into at least 100,000 or more beneficiary cells Kumar Jeetendra | January 1, 2021 Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput way of transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders. A study, published …
Sloan Kettering Institute specialists offer news answer to 100-year-old malignancy secret Kumar Jeetendra | January 23, 2021 The year 2021 marks the 100th anniversary of a basic discovery that is taught in every biochemistry textbook. In 1921, German doctor Otto Warburg observed that cancer cells harvest energy from sugar sugar in a strangely inefficient manner: instead of”burn” it using cancer cells do what yeast do — they ferment it. This oxygen-independent process …
Study shows why children of obese moms have inclination to create metabolic illnesses Kumar Jeetendra | January 27, 2021 A Brazilian study published in the journal Molecular Human Reproduction helps understand why overweight mothers often have children with a propensity to develop metabolic disease during their lifetime, according to previous research. According to the authors,”transgenerational transmission of metabolic disorders” may be associated with Mfn2 deficiency in the mother’s oocytes (immature eggs). Mfn2 refers to …
Scientists concentrate what the methylation of proteins means for various mitochondrial measures Kumar Jeetendra | February 21, 2021 Diseases of the cells’ energy supply can cause a range of serious ailments, but also appear to be connected to aging. More research is required on mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet reveals how an important molecule inside the mitochondria affects their function in mice and fruit …
Dietary components hold guarantee for working on the health and wellbeing of grown-ups Kumar Jeetendra | January 26, 2022 Research suggests that nutritional supplements that target specific mechanisms that are associated with age-associated cellular decay (AACD), have the potential to improve health and well-being for adults. “Cellular Nutrition and Its Influence on Age-Associated Cellular Decline,” the latest issue of The Gerontological Society of America’s What’s Hot newsletter with accompanying infographic, provides an overview of …