From Bacteria to Humans: Do Prokaryotes Have Mitochondria? Kumar Jeetendra | November 17, 2025 There is one fact about life on Earth we cannot escape: each and every biological organism, no matter the size and complexity, is run by microscopic biological machines. In the case of larger, more complex organisms, those machines are called mitochondria–the powerhouses of the cell. But what about bacteria, the highly diverse ancient prokaryotes? Do …