Possible connect to brain irritation may clarify the association among MS and exhaustion Kumar Jeetendra | August 27, 2020 As much as 60 percent of individuals with multiple sclerosis (MS) report that fatigue is that the disease’s most distressing symptom. And fatigue remains among MS’s puzzles — despite its incidence and significance, the root cause of this symptom remains unclear. In a study published in Neurology Neuroimmunology & Neuroinflammation, investigators from Brigham and Women’s …
Study gives conceivable clarification to reformist course of different sclerosis in mice Kumar Jeetendra | October 17, 2020 People with multiple sclerosis (MS) gradually develop increasing functional impairment. Researchers at Karolinska Institutet in Sweden have found a possible explanation for the progressive course of this disease in mice and how it can be reversed. The analysis, which is published in Science Immunology, can prove beneficial to future treatments. MS is a chronic inflammatory …
Myeloid cells can smother insusceptible reaction, advance cerebrum metastasis Kumar Jeetendra | October 28, 2020 Scientists have long thought that the brain protects itself from an aggressive immune response to keep inflammation down. However, that evolutionary management may work against it when a cancer cell tries to spread to the brain, researchers at the University of Notre Dame have found. In recently published research in the journal Cell, researchers showed …
Trinity crew uncovers mutations connected with early onset dementia Kumar Jeetendra | December 22, 2020 Researchers at Trinity College Dublin today announced a significant advance in our knowledge of an early onset form of dementia which may also advance our understanding of conditions such as Alzheimer’s disease. Adult onset Leukoencephalopathy with axonal Spheroids and Pigmented glia (ALSP) is an ultra-rare condition characterized by mutations in a gene named Colony stimulating …
Researchers locate mechanism underlying plasticity in grownup brains Kumar Jeetendra | December 27, 2020 Developing brains continuously sprout new neuronal connections called synapses as they understand and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while links deemed unnecessary are pruned away. Adult brains experience similar pruning, but it was unclear why or how synapses in …
Study recognizes specific immune cells that shape inhibitory neurons to control mind wiring Kumar Jeetendra | July 7, 2021 Every second our brains are exposed to a variety of signals, from the barking of a puppy to raindrops hitting the windows, and everything in between. Most of the time we ignore insignificant cues like the buzzing of a fly or the gentle rustle of leaves in a tree. We pay attention to the more …
Small molecule drug can weaken the triggers of neuroinflammation, preclinical review shows Kumar Jeetendra | September 24, 2021 Neuroinflammation may cause worse outcomes in cases of stroke, injuries to the brain or injury, and can increase the severity of neurodegenerative diseases such as ALS, Parkinson’s, or Alzheimer’s. This suggests that reducing neuroinflammation might be an exciting new method to treat neurological disorders and neuropathic pain caused by neuroinflammation. In a preclinical study , …
