Estradiol and Weight Gain: What’s the Real Story? Kumar Jeetendra | April 15, 2025 We all wonder at some point if hormones, for instance, estradiol, could be affecting our weight in one way or another. Well, you are not alone. Estradiol, one of the forms of estrogen, is extremely critical for the female reproductive system but does not end its impact there. This hormone definitely has a wide range …