Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells Kumar Jeetendra | July 20, 2020 Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes caused by a drug (amiodarone) in human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe. This was achieved at the Multimode InfraRed Imaging and Micro-Spectroscopy (MIRIAM) beamline (B22) …
Researchers devise new technique to plan HIV’s sweet shield in remarkable detail Kumar Jeetendra | October 26, 2020 Scientists from Scripps Research and Los Alamos National Laboratory have devised a method for mapping in unprecedented detail the thickets of slippery sugar molecules which help protect HIV from the immune system. Mapping these shields will give researchers a more comprehensive comprehension of why dinosaurs respond to some spots on the virus but not others, …
Cell scientists and bioimaging master collaborate to settle fourth measurement insider facts Kumar Jeetendra | October 29, 2020 Cell biologists at the University of Illinois in Urbana-Champaign and Bar-Ilan University in Israel and a bioimaging expert at the University of Central Florida are teaming up in what they expect may result in a major breakthrough in the understanding of the three-dimensional organization of the nucleus over their role in certain diseases. The dream …
New UCLA-formed gadget moves mitochondria into at least 100,000 or more beneficiary cells Kumar Jeetendra | January 1, 2021 Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput way of transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders. A study, published …
Biomarkers can foresee how hereditarily identical cells act distinctively under pressure Kumar Jeetendra | January 10, 2021 A set of biomarkers not traditionally associated with cell fate can accurately forecast how genetically identical cells behave differently under pressure, according to a UT Southwestern study. The findings, published by Cell Reports as a Dec. 1 cover story, could eventually result in more predictable responses to pharmaceutical remedies. Groups of the same types of …
