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    Malignant

    Scientists distinguish new method that causes leukemia

    Every year, 1.1 million new cases of blood cancers are diagnosed globally. Currently, chemotherapy remains the most common and efficient plan of treatment. On the other hand, the development of aggressive types of leukemia in adults stimulates a need for early detection and new therapeutic approaches to achieve better clinical outcomes. In a novel step

    Hematoxylin compounds can specifically kill CALR mutant cancer cells

    Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Researchers of the research team of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the

    Hematoxylin compounds can specifically kill CALR freak disease cells

    Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the

    New UCLA-formed gadget moves mitochondria into at least 100,000 or more beneficiary cells

    Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput way of transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders. A study, published

    Gene panel test empowers exceptionally exact diagnosis of liposarcomas

    Scientists have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel evaluation which allows for highly accurate diagnosis of the most frequent kinds of liposarcoma. The new assay is described in The Journal of Molecular Diagnosis, published by Elsevier. Liposarcomas are a type of malignant cancer that is

    Bacteria residing within inside tumor cells can support malignant growth immunotherapy

    Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. The study may also help clarify the connection between immunotherapy and the intestine microbiome, describing the findings of earlier research that the microbiome impacts the success of immunotherapy. Immunotherapy remedies of the last decade or so have dramatically improved healing

    MRI screening and designated biopsies could diminish overdiagnoses of prostate malignant growth

    Many countries do not have nationwide prostate-cancer screening. Current methods lead to overdiagnoses, unnecessary biopsies, and unnecessary biopsies. Researchers at Karolinska Institutet, Sweden, have published a new study in The New England Journal of Medicine. It shows that targeted biopsies and magnetic resonance imaging (MRI), could reduce overdiagnoses by up to half. These results were