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    Malaria

    Seeing how the malaria can withstand fever’s warmth

    Even when a man suffering from malaria is burning up with fever and too ill to operate, the little blood-eating parasites lurking inside them continue to flourish, relentlessly growing and multiplying as they gobble up the host’s red blood cells. The single-celled Plasmodium parasites that cause 200 million cases of malaria annually can withstand feverish

    Female mosquitoes can distinguish a mix of four unique substances in blood

    Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Researchers are learning what people taste like to mosquitoesdown to the individual neurons that sense blood’s distinctive, flavorful taste. Female mosquitoes have a sense of taste that is especially tuned to detect a combination of

    Researchers propose that antimalarial medications could be repurposed to treat COVID-19

    An international group of researchers believe there is enough evidence that anti-malarial drugs could be repurposed to treat COVID-19 and they need to be evaluated for efficacy in clinical trials. The review article, published online in Trends in Parasitology, summarizes the evidence for its antiviral and anti-inflammatory properties of particular anti-malarial drugs which could play

    Drug-discovery collaboration discovers potential new antimalarial drug candidates

    Potential new antimalarial drug candidates are being developed through an protracted drug-discovery collaboration between Australian medical research institute WEHI and Janssen Pharmaceutica NV. The collaboration was facilitated by Johnson & Johnson Innovation. A collaborative research team discovered compounds with antimalarial activity within a collection of 80,000 drug-like molecules at the Janssen Jump-stARter Compound Library, a

    Study gives significant knowledge to forestalling worldwide pandemics

    Whether it’s plankton exposed to parasites or people exposed to pathogens, a host’s initial immune response plays an integral role in determining whether infection occurs and to what level it spreads within a population, new University of Colorado Boulder research indicates. From parasitic flatworms transmitted by snails into individuals in developing nations, to zoonotic spillover

    First CRISPR-Cas9-based gene drive cuts and duplicates hereditary components in Arabidopsis plants

    University of California San Diego scientists developed the first CRISPR/Cas9 based gene drive in plants. Their goal is to breed resilient crops that can withstand drought and diseases. Although gene drive technology for insects has been created to stop the spread and transmission of vector-borne diseases like Malaria, scientists in Professor Yunde Zha’s lab along

    Pharmaceutical Roots: Malaria, from Bugs to Drugs

    Pharmaceutical Roots is a content series from LGC Mikromol investigating and outlining the natural origins of pharmaceutical substances, and offering a deeper dive into their uses, risks, and mechanisms of action. In the first article of our new Bugs to Drugs sister series, we turn the spotlight on almost 350 years of developing medicines to fight