A tale technique to accomplish site-particular chiral tranquilize union in living frameworks Kumar Jeetendra | June 27, 2020 Enantioselectivity assumes a significant job in the pharmacological and toxicological procedures of chiral drugs. In chiral tranquilize combination that utilizes bioorthogonal science inside complex organic milieu, deviated move hydrogenation (ATH), which uses safe hydrogen givers rather than high weight H2, has been picking up ubiquity and has been acted in living cells. Prof. QU Xiaogang …
Study shows how mast cells manage calcium levels to control the invulnerable reaction Kumar Jeetendra | July 23, 2020 Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune disorders and allergies. An Ludwig-Maximilian-Universitaet (LMU) in Munich group has dissected how mast cells modulate their calcium levels to maintain the immune response under control. The immune system defends us against attack by germs and viruses and also …
Biomedical scientists make counterfeit organelles to control biological function in cells Kumar Jeetendra | August 7, 2020 Biomedical engineers at Duke University have shown a way of controlling the phase separation of an emerging class of proteins to create artificial membrane-less organelles in human cells. The progress, similar to controlling how vinegar forms droplets within oil, creates chances for engineering artificial structures to modulate present cell functions or produce entirely new behaviours …
Examination shows how a protein prevents cells from assaulting their own DNA Kumar Jeetendra | August 20, 2020 Viruses multiply by injecting their DNA into a host cell. Once it passes the intracellular fluid, then this foreign substance triggers a defense mechanism referred to as the cGAS-STING pathway. This, in turn, binds to another protein named Stimulator of Interferon Genes (STING), which induces an inflammatory immune reaction. From time to time, the material …
New polygenic danger score to help foresee the chances of medications causing liver harm Kumar Jeetendra | September 20, 2020 The ancient Romans studied the livers of sacrificial animals to read omens and create prophesies. Researchers at Tokyo Medical and Dental University (TMDU) and Takeda-CiRA program alongside a world-wide group of collaborators, have devised a polygenic risk score (PRS) based on liver genomics that can predict the probability of medications causing liver damage. Adding new …
New consortium aims to comprehend principles underlying the formation of coronaviruses Kumar Jeetendra | December 10, 2020 “This consortium will aim to comprehend the physical principles underlying the formation of coronaviruses,” said Roya Zandi, a professor of physics and astronomy at UC Riverside and the principal investigator of this four-year project that received funding of over $1.75 million. “We will also explore the effect of some drugs on the assembly process.” Zandi …
Biomarkers can foresee how hereditarily identical cells act distinctively under pressure Kumar Jeetendra | January 10, 2021 A set of biomarkers not traditionally associated with cell fate can accurately forecast how genetically identical cells behave differently under pressure, according to a UT Southwestern study. The findings, published by Cell Reports as a Dec. 1 cover story, could eventually result in more predictable responses to pharmaceutical remedies. Groups of the same types of …
An upgraded interaction to detach and cleanse magnetic nanoparticles Kumar Jeetendra | February 20, 2021 Magnetic nanoparticles biosynthesized by germs might soon play an significant role in biomedicine and biotechnology. Researchers at the University of Bayreuth have developed and optimized a procedure for the purification and isolation of the particles from bacterial cells. In initial tests, magnetosomes showed good biocompatibility when compared with human cell lines. The results presented in …
Researchers examine signal necrotic cells that prompt phagocytic cells to overwhelm the dying cell Kumar Jeetendra | May 8, 2021 As people keep their homes clean and clutter in check, a crew of cells within the body is in charge of clearing the waste that the body generates, including cells that are dying. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means’eating cells’ “Phagocytosis is quite important for the body’s …
