CRISPR-based framework smothers qualities identified with AAV antibody production Kumar Jeetendra | September 9, 2020 Gene therapy generally is based on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the event of CRISPR-based gene therapies, molecular scissors can then snip out a faulty gene, add in a missing arrangement or enact a temporary change in its expression, but the body’s immune response to AAV can …
Researchers use quality treatment to recover harmed optic nerve filaments Kumar Jeetendra | November 5, 2020 Scientists have used gene therapy to regenerate damaged nerve fibers from the eye, in a discovery that could aid the development of new treatments for glaucoma, one of the main causes of blindness worldwide. Axons – nerve pathways – in the adult central nervous system (CNS) do not normally regenerate after injury and disease, meaning …
New information shows empowering results for patients with neuro-degenerative blinding eye illness Kumar Jeetendra | December 16, 2020 New data published in the Journal Science Translational Medicine shows encouraging results in a worldwide clinical trial for patients diagnosed with the neuro-degenerative blinding eye disease; Leber Hereditary Optic Neuropathy (LHON. The disease is an inherited type of vision loss estimated to affect 1 in 30,000 to 50,000 individuals. LHON most often afflicts individuals with …
new cGMP plasmid DNA manufacturing facility construction announced by Thermo Fisher Kumar Jeetendra | December 18, 2020 Thermo Fisher Scientific, the world leader in serving science, today announced the construction of a new cGMP plasmid DNA manufacturing facility in Carlsbad, Calif. The site will expand the company’s clinical and commercial capabilities for cGMP plasmid DNA used as a critical raw material to develop and manufacture cell and gene-based therapies including life-saving cancer …
Gene therapy can viably treat mice with tuberous sclerosis complex, shows study Kumar Jeetendra | January 9, 2021 Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in several organs of the body, have limited treatment choices. A team led by investigators at Massachusetts General Hospital (MGH) has shown that gene therapy can effectively treat mice that express one of the mutated genes that cause the disease. …
New gene based vaccine procedure gets award from the Bill and Melinda Gates Foundation Kumar Jeetendra | January 29, 2021 The AAVCOVID vaccine application, a novel gene-based vaccine plan that utilizes an adeno-associated virus (AAV) vector, was granted an award for up to $2.1 million from the Bill & Melinda Gates Foundation. The grant will assist the effort to bring further preclinical validation into the AAV vaccine platform. An AAVCOVID vaccine candidate is set to …
Researchers develop experimental direct-acting antiviral treatment to treat COVID-19 Kumar Jeetendra | May 18, 2021 An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19. Conventional antivirals reduce symptoms and help people recover earlier. Examples …
Analysts study the role of subnuclear NSrp70 in T cell-intervened adaptive immunity Kumar Jeetendra | July 15, 2021 T cell are part of the body’s immune response. The way proteins are spliced in their development and maturation determines how T cells can recognize different pathogens and mount defense against them. Scientists from Korea now highlight the role of NSrp70 in regulating maturation. This protein was previously found in T cells subnuclear space and …
Vaccizone selects Exothera for process development and GMP manufacturing of its SARS CoV 2 vaccine based on proprietary ASC technology Kumar Jeetendra | July 14, 2022 Istanbul (Turkey) – 6th July 2022 – Life Science Newswire – Vaccizone, a vaccine development company focusing on innovative antigen delivery technology, selected Exothera S.A. to fast-track process development of its SARS CoV 2 vaccine for European clinical trials. Vaccizone has developed and patented a novel method for delivering antigens and bioactive compounds which can …
Cell and Gene Therapy: Pros and Cons Everyone Should Know Kumar Jeetendra | July 11, 2023 Biopharmaceutical firms are undergoing a paradigm shift as a result of ongoing developments in cell and gene therapy (CGT), which has the potential to heal certain diseases. Both cell therapy and gene therapy are subspecialties that fall under the umbrella of the broader discipline of gene therapy. Both treatments have the goal of treating, preventing, …
Affordable gene and cell therapies need of the hour: Dr Kapil Bharti Kumar Jeetendra | August 22, 2023 Eyestem Research, a pioneering cell therapy company with a vision to democratise access to cutting-edge technologies for the bottom 99% of the global population, hosted the inaugural Foresight 2023 summit, India’s first retinal cell and gene therapy conference. Held in Bengaluru on 17th and 18th August 2023, the Foresight 2023 summit was co-hosted by inStem …
Cell culture: Techniques, Errors and Equipments used Kumar Jeetendra | September 3, 2023 Growing and maintaining cells in a laboratory-controlled setting is known as cell culture. Numerous scientific disciplines, including cell biology, cancer research, drug discovery, and tissue engineering, greatly benefit from this method. Cell Culture Techniques: Cell Line Selection: Researchers choose a specific cell line based on their research objectives. Cell lines can be primary (isolated directly …
