Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells Kumar Jeetendra | July 20, 2020 Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes caused by a drug (amiodarone) in human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe. This was achieved at the Multimode InfraRed Imaging and Micro-Spectroscopy (MIRIAM) beamline (B22) …
Researchers devise new technique to plan HIV’s sweet shield in remarkable detail Kumar Jeetendra | October 26, 2020 Scientists from Scripps Research and Los Alamos National Laboratory have devised a method for mapping in unprecedented detail the thickets of slippery sugar molecules which help protect HIV from the immune system. Mapping these shields will give researchers a more comprehensive comprehension of why dinosaurs respond to some spots on the virus but not others, …
A short-reduce in photosynthetic equipment can permit needles of pine bushes to live green Kumar Jeetendra | December 24, 2020 How do conifers which are used for example as Christmas trees keep their green needles over the boreal winter when many trees drop their leaves? Science hasn’t provided a good response to this question but now an international group of scientists, including researchers in Umeå University, has deciphered that a short-cut in the photosynthetic machinery …
Scientists disentangle the cycle that makes virus irresistible Kumar Jeetendra | January 9, 2021 Researchers have for the first time identified how viruses like the poliovirus and the common cold virus’package up’ their genetic code, allowing them to infect cells. The findings, published today (Friday, 8 January) in the journal PLOS Pathogens by a team from the Universities of Leeds and York, open up the possibility that medication or …
New fluorescence microscopy strategy produces nanoscale 3D pictures of living cells Kumar Jeetendra | January 12, 2021 A new fluorescence microscopy technique has produced the world’s first nanoscale 3D images of molecules in a whole, living cell, researchers at KTH Royal Institute of Technology reported. Ilaria Testa, an associate professor at KTH and researcher at the Science for Life Laboratory, says the technique is capable of generating images with precision that until …
Small SARS-CoV-2 protein may have huge ramifications for future COVID-19 medicines Kumar Jeetendra | April 12, 2021 A very small protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future therapies, according to a team of Penn State researchers. Using a novel toolkit of approaches, the scientists uncovered the first full structure of the Nucleocapsid (N) protein and discovered how antibodies from COVID-19 patients interact with …
Researchers enlighten how a few antibodies can viably disable ebolaviruses Kumar Jeetendra | April 18, 2021 Some survivors of ebolavirus outbreaks create antibodies that may broadly neutralize those viruses–and today , scientists at Scripps Research have illuminated how these antibodies can disable the viruses so efficiently. The insights might be helpful for developing effective treatments. Ebolavirus is a family of often-deadly viruses that includes Ebola virus and lots of lesser-known viruses …
New system joins PC programming and cryo-EM to decide 3D constructions of RNA-only molecules Kumar Jeetendra | August 16, 2021 The single-stranded gene material RNA, also known as RNA, is most well-known for its ability to guide the assembly of proteins and carry the genetic code for viruses such as HIV and SARS-CoV-2. Scientists discovered a hidden talent 40 years ago: It can catalyze chemical reaction in cells, including joining and snipping RNA strands. This …
