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    DNA Damage

    Oregon scientists uncover sub-atomic instruments that produce DNA harm in sperm

    University of Oregon biologists have used the model organism Caenorhabditis elegans to identify molecular mechanisms that produce DNA damage in sperm and contribute to male infertility following exposure to heat. In humans, the optimal temperature for sperm production is just below body temperature, in a range of approximately 90-95 degrees F. Human studies have found

    Researchers utilize funtional test to quantify the impact of inhertited varient in BRCA2 acancer gene

    Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variations in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS). The findings were published today in a study

    Researchers examine how oxygen radicals secure against cancer

    Initially, oxygen radicals – reactive oxygen species, or ROS for short – were thought of as exclusively harmful in the body. They’re produced, by way of example, by smoking or UV radiation. Because of their high reactivity, they could damage many important molecules in cells, including the hereditary molecule DNA. As a result, there’s a