Identifying contaminants in a cell culture lab Kumar Jeetendra | June 6, 2022 Contaminants are most commonly of biological nature and can include bacteria, fungi, viruses, and parasites. It is important to limit biological contaminants since they can alter the phenotype and genotype of the cultured cell line through competition for nutrients, synthesis of alkaline, acidic or toxic by-products, and the potential interference of viral components with the …