Researchers propose that antimalarial medications could be repurposed to treat COVID-19 Kumar Jeetendra | October 20, 2020 An international group of researchers believe there is enough evidence that anti-malarial drugs could be repurposed to treat COVID-19 and they need to be evaluated for efficacy in clinical trials. The review article, published online in Trends in Parasitology, summarizes the evidence for its antiviral and anti-inflammatory properties of particular anti-malarial drugs which could play …
Antenatal steroids improve preterm infant endurance in low-asset settings, discovers study Kumar Jeetendra | October 24, 2020 The results of a new clinical trial, published today in the New England Journal of Medicine, show that dexamethasone- a glucocorticoid used to treat many conditions, including rheumatic problems and severe COVID-19- may boost survival of premature babies when given to pregnant women at risk of premature birth in low-resource settings. The WHO ACTION-I trial …
Dexamethasone use could reduce immune checkpoint inhibitor viability in glioblastoma patients Kumar Jeetendra | November 25, 2020 Bottom Line: One of patients with glioblastoma getting an immune checkpoint inhibitor, people who obtained the corticosteroid dexamethasone at baseline for cerebral edema had significantly worse overall survival. Journal Where the Study was Released: Clinical Cancer Research, a journal of the American Association for Cancer Research Author: David A. Reardon, MD, clinical director of the …
Researchers develop little intestinal cells from human-actuated pluripotent stem cells Kumar Jeetendra | February 8, 2021 A group of scientists from Japan have found success in growing small intestinal cells, akin to those found in the human body, from human-induced pluripotent stem cells. They assert that the grown cells may be used for laboratory studies focusing on human small intestinal drug metabolism and transport. Because of this, studies on the absorption …
