Trinity crew uncovers mutations connected with early onset dementia Kumar Jeetendra | December 22, 2020 Researchers at Trinity College Dublin today announced a significant advance in our knowledge of an early onset form of dementia which may also advance our understanding of conditions such as Alzheimer’s disease. Adult onset Leukoencephalopathy with axonal Spheroids and Pigmented glia (ALSP) is an ultra-rare condition characterized by mutations in a gene named Colony stimulating …
Researchers locate mechanism underlying plasticity in grownup brains Kumar Jeetendra | December 27, 2020 Developing brains continuously sprout new neuronal connections called synapses as they understand and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while links deemed unnecessary are pruned away. Adult brains experience similar pruning, but it was unclear why or how synapses in …
Individuals with vision impedance have higher risk of all-cause mortality Kumar Jeetendra | March 6, 2021 The global population is aging, and so are their eyes. In fact, the number of individuals with vision impairment and blindness is expected to more than double over the next 30 years. A meta-analysis in The Lancet Global Health, comprising 48,000 individuals from 17 studies, found that those with more severe vision impairment had a …
Imbalanced bacterial community in the gums connected to Alzheimer’s infection biomarker Kumar Jeetendra | April 12, 2021 Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta–a key biomarker for Alzheimer’s disease–in their cerebrospinal fluid (CSF), according to new research from NYU College of Dentistry and Weill Cornell Medicine. However, this imbalance in oral bacteria was not associated with another Alzheimer’s biomarker …