Improving affectability of fluid biopsy utilizing ‘inexactly stacked’ identification layers Kumar Jeetendra | November 4, 2020 By detecting DNA fragments in body fluids like urine, some kinds of cancer may already be tracked in an early stage. But in order to capture them, detection sensitivity must be improved. Researchers at the University of Twente in The Netherlands (MESA+ Institute) use electrically charged polymers for this. Not only one layer of this, …
Study famous how ecDNA fragments pressure gene amplification to generate drug resistance in cancer Kumar Jeetendra | December 26, 2020 Researchers headed by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the puzzle of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to create drug resistance in cancer. The study, published on December 23 in the journal Nature, provides new …
The Cancer Microbiome Atlas gives more clear picture of microbiota living in organs Kumar Jeetendra | January 14, 2021 Biomedical engineers at Duke University have devised an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). With a clearer picture of the microbiota living in a variety of organs in both healthy and cancerous states, researchers will now have the ability to find new biomarkers of disease and better understand …
Daily aspirin can lessen danger of colorectal disease in adults Kumar Jeetendra | January 22, 2021 Regular aspirin use has clear benefits in reducing colorectal cancer incidence among middle-aged adults, but also comes with some risk, such as gastrointestinal bleeding. And when should adults start taking regular aspirin and for how long? There is substantial evidence that a daily aspirin can reduce risk of colorectal cancer in adults up to age …
Hereditary components of human gut microbiota are key to wellbeing Kumar Jeetendra | February 6, 2021 Neanderthals’ gut microbiota already contained some beneficial micro-organisms that are also found within our own intestine. An international research group headed by the University of Bologna achieved this result by extracting and analyzing ancient DNA from 50,000-year-old fecal sediments sampled at the archaeological site of El Salt, near Alicante (Spain). Published in Communication Biology, their …
Researchers describe the systems that manage embryonic stem cells Kumar Jeetendra | March 26, 2021 Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have clarified the mechanisms, unknown to date, included in maintaining embryonic stem cells in the best possible condition for their use in regenerative medicine. The results, published in Nature Communications, helps to find novel stem-cell therapies for …
Researchers develop another approach to grow little pancreas replicas Kumar Jeetendra | September 14, 2021 In collaboration with Cancer Research UK Manchester Institute scientists, engineers from MIT have created a new method to create tiny replicas of pancreas using healthy and cancerous pancreatic cell lines. These models could be used by researchers to test and develop potential treatments for pancreatic cancer. This is one of the most difficult types. Researchers …