Test mRNA-based COVID-19 immunization evokes defensive safe reactions in animals Kumar Jeetendra | July 25, 2020 Two injections of this vaccine were enough to induce robust immunity, completely preventing SARS-CoV-2 infection in mice. MRNA-based vaccines are all attractive options for protecting against SARS-CoV-2 because they may be quickly designed and manufactured at a huge scale within weeks. Moreover, preclinical studies have shown that mRNA-based vaccines cause potent and broadly protective immune …
new cGMP plasmid DNA manufacturing facility construction announced by Thermo Fisher Kumar Jeetendra | December 18, 2020 Thermo Fisher Scientific, the world leader in serving science, today announced the construction of a new cGMP plasmid DNA manufacturing facility in Carlsbad, Calif. The site will expand the company’s clinical and commercial capabilities for cGMP plasmid DNA used as a critical raw material to develop and manufacture cell and gene-based therapies including life-saving cancer …
Researchers find out protein that adjusts gene interest to healthy nutrient stages in roundworms Kumar Jeetendra | December 23, 2020 Changing a fertilized egg into a fully functional adult is a complicated endeavor. Cells must split, move, and mature at specific times. Developmental genes control that process, turning on and off at a choreographed way. However, the environment affects development. They discovered a master switch developing worms use to pause growth when nutrients are scarce. …
A short-reduce in photosynthetic equipment can permit needles of pine bushes to live green Kumar Jeetendra | December 24, 2020 How do conifers which are used for example as Christmas trees keep their green needles over the boreal winter when many trees drop their leaves? Science hasn’t provided a good response to this question but now an international group of scientists, including researchers in Umeå University, has deciphered that a short-cut in the photosynthetic machinery …
Scientists disentangle the cycle that makes virus irresistible Kumar Jeetendra | January 9, 2021 Researchers have for the first time identified how viruses like the poliovirus and the common cold virus’package up’ their genetic code, allowing them to infect cells. The findings, published today (Friday, 8 January) in the journal PLOS Pathogens by a team from the Universities of Leeds and York, open up the possibility that medication or …
Jellagen dispatches JellaGel™, the principal Collagen Type 0 Hydrogel taking available driving Extracellular Matrix Kumar Jeetendra | January 15, 2021 Jellagen® Limited, a biotechnology company manufacturing high-value Collagen Type 0 derived from jellyfish, announce the launch of their JellaGel™ Hydrogel. 3-dimensaional Hydrogels make it possible for cells to grow and interact with all of their surroundings that makes a massive difference. Cells grown in a 3D model have been shown to be more natural, with …
Researchers produce first African lion in-vitro embryos after vitrification of juvenile oocytes Kumar Jeetendra | January 18, 2021 A team of scientists from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) in Germany, Givskud Zoo – Zootopia in Denmark and the University of Milan in Italy succeeded in producing the very first African lion in-vitro embryos after the vitrification of immature oocytes. For this specific method of cryopreservation, oocytes are collected right …
Bacteria responsible for seafood related stomach disturbs can go torpid and “wake up” Kumar Jeetendra | January 20, 2021 Vibrio parahaemolyticus is a marine bacterium that can lead to gastroenteritis in humans when eaten in raw or undercooked shellfish such as oysters and mussels. Some of these bacteria have the ability to turn dormant in poor growth conditions such as cold temperatures – and can stay in that state of hibernation for long periods …
New gene based vaccine procedure gets award from the Bill and Melinda Gates Foundation Kumar Jeetendra | January 29, 2021 The AAVCOVID vaccine application, a novel gene-based vaccine plan that utilizes an adeno-associated virus (AAV) vector, was granted an award for up to $2.1 million from the Bill & Melinda Gates Foundation. The grant will assist the effort to bring further preclinical validation into the AAV vaccine platform. An AAVCOVID vaccine candidate is set to …
New testing protocols for SARS-CoV-2 can handle a huge number of tests inside 48 hours Kumar Jeetendra | May 25, 2021 Researchers in the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is printed in the journal Nature Communications and might be adapted to many more pathogens. The COVID-19 pandemic has lasted more than a year and continues to …
Castration of male sheep eases back DNA maturing Kumar Jeetendra | July 6, 2021 We all know that women live longer lives than men. If we told you that there were one way to prolong your life, would you listen? Researchers from University of Otago and collaborators from the United States published a study in ELife today. It showed that castration of male sheep slows down DNA’s aging and …