Scientists distinguish new method that causes leukemia Kumar Jeetendra | August 13, 2020 Every year, 1.1 million new cases of blood cancers are diagnosed globally. Currently, chemotherapy remains the most common and efficient plan of treatment. On the other hand, the development of aggressive types of leukemia in adults stimulates a need for early detection and new therapeutic approaches to achieve better clinical outcomes. In a novel step …
New T-cell-based immunization procedure gives more extensive insurance against occasional flu Kumar Jeetendra | September 24, 2020 As Americans begin pulling their sleeves up for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternate vaccine approach that provides wider protection against seasonal flu. In a study published in Cell Reports Medicine today (Sept. 22), scientists describe a T-cell-based vaccine strategy that’s effective against multiple …
Chemists propose another domino response to deliver organic compound against cancers Kumar Jeetendra | October 12, 2020 A group of chemists in RUDN University suggested a new response to produce organic compounds in 1 vessel. The end products proven to be effective against the cells of carcinomas, including drug-resistant ones. The new reaction was explained from the Bioorganic Chemistry journal. For many organic substances synthesis is a multistage process of step-by-step molecule …
Researchers find out how shattered chromosomes make most cancers cells greater aggressive Kumar Jeetendra | December 27, 2020 Cancer is one of the world’s biggest health afflictions because, unlike some diseases, it’s a moving target, constantly evolving to evade and resist treatment. In a paper published in the December 23, 2020 online dilemma of Nature, researchers at University of California San Diego School of Medicine and the UC San Diego branch of the …
Surgery may expand length of endurance for metastatic breast malignant growth patients Kumar Jeetendra | December 28, 2020 They studied nearly 13,000 stage four breast cancer patients and found that those who had surgery as well as their other remedies had a survival advantage over those who had other therapies alone. Stage four breast cancer accounts for 6% of newly-diagnosed breast cancer cases. Systemic treatment, which may include treatments like chemotherapy, hormone therapies …
New upkeep treatment for AML shows solid advantage for patients Kumar Jeetendra | January 23, 2021 Patients with acute myeloid leukemia (AML), the most common form of leukemia in adults, that has gone into remission following initial chemotherapy remain in remission longer and have improved overall survival when they are given a pill form of the cancer drug azacitidine as a maintenance therapy, based on a randomized, international phase 3 clinical …
Study describes cisplatin-prompted hearing loss in pediatric cancer growth patients Kumar Jeetendra | February 14, 2021 Permanent hearing loss is a common side effect of the medicine, but until now, studies have been too little and too varied to accurately characterize this risk. Today in The Lancet Child & Adolescent Health, researchers at Children’s Hospital Los Angeles published results of the biggest analysis of cisplatin-induced hearing loss to date. The analysis …
Study shows the effect of ‘reverse antibiotic’ on gram-negative bacteria Kumar Jeetendra | March 5, 2021 Researchers from Skoltech and MSU have investigated antibiotic nybomycin that could prove effective against bacteria resistant to other antibiotics. Their research was published in the journal Antimicrobial Agents and Chemotherapy. All bacterial cells contain topoisomerases, a significant group of enzymes that help deal with spatial problems stemming from bacterial cell division related to circular DNA …
Study maps design and system of a membrane enzyme that assumes part in inflammation, cancer Kumar Jeetendra | March 21, 2021 Most drugs operate via the membranes that surround the body’s cells. The analysis, which is printed in the journal Nature Communications, can make a significant contribution to the development of potential drugs. The cells’ equal to organs, the organelles, are enclosed by membranes. Embedded in the cell’s external and internal membranes are proteins that regulate …
Pharmaceutical Roots: etoposide – the winding road from folk remedy to chemotherapy drug Kumar Jeetendra | August 9, 2023 Etoposide is a leading chemotherapy drug used widely in cancer treatment – but in particular against testicular and small cell lung cancer, which together account for more than 400,000 new cases worldwide each year. Although sourced from a plant used to treat many ailments for centuries, its development as an antineoplastic drug was “very tortuous” …
