Examination shows how a protein prevents cells from assaulting their own DNA Kumar Jeetendra | August 20, 2020 Viruses multiply by injecting their DNA into a host cell. Once it passes the intracellular fluid, then this foreign substance triggers a defense mechanism referred to as the cGAS-STING pathway. This, in turn, binds to another protein named Stimulator of Interferon Genes (STING), which induces an inflammatory immune reaction. From time to time, the material …
New comprehension of physical properties of chromatin may show how genome is encoded and decoded Kumar Jeetendra | December 21, 2020 University of Alberta researchers have found an answer to a basic question in genomic biology that has eluded scientists because the discovery of DNA: Over the nucleus of our cells, is the complex package of DNA and proteins called chromatin a solid or a liquid? Previously, fields like biochemistry operated under the premise that chromatin …
Analysts recognize interface among ALS and collection of DNA-RNA hybrids in the genome Kumar Jeetendra | January 13, 2021 Researchers from the University of Seville and the University of Pavia have identified a connection between Amyotrophic Lateral Sclerosis (ALS) and the accumulation of DNA-RNA hybrids in the genome. The accumulation of these hybrids causes increased genomic damage and boosts genetic instability. This finding will make it possible to better understand the molecular basis of …
Protein alteration adds to degeneration of neuronal populaces in Huntington’s infection Kumar Jeetendra | February 1, 2021 A study in which UB scientists have taken part states that alterations in the levels of one of those proteins, lamin B1, add to the degeneration of distinct brain neuronal populations in Huntington’s disease. Caused by a mutation in the huntingtin gene, this pathology features involuntary movements, cognitive deficit, and psychiatric disorders, and has no …
New examination reveals insight into complex brain measure that learns and structure new memories Kumar Jeetendra | April 19, 2021 Making memories involves over seeing friends or taking photos. How neurons do so –reaching out arm-like dendrites to communicate with other neurons–requires a ballet of genes, signaling molecules, cellular scaffolding and protein-building machinery. A new study from scientists at Scripps Research and the Max Planck Florida Institute for Neuroscience finds a fundamental role for one …
Researchers examine how oxygen radicals secure against cancer Kumar Jeetendra | April 26, 2021 Initially, oxygen radicals – reactive oxygen species, or ROS for short – were thought of as exclusively harmful in the body. They’re produced, by way of example, by smoking or UV radiation. Because of their high reactivity, they could damage many important molecules in cells, including the hereditary molecule DNA. As a result, there’s a …
Study uncovers the complex cell mechanism of Ebola Kumar Jeetendra | July 8, 2021 Mount Sinai researchers discovered the intricate cellular mechanisms of Ebola virus. This could help to explain the severe effects on people and provide potential treatment or prevention. The team published a study in mBio that showed how VP24, a protein from the Ebola virus interacts with the double-layered cell membrane (known as the nucleus) and …