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    Cell Nucleus

    Examination shows how a protein prevents cells from assaulting their own DNA

    Viruses multiply by injecting their DNA into a host cell. Once it passes the intracellular fluid, then this foreign substance triggers a defense mechanism referred to as the cGAS-STING pathway. This, in turn, binds to another protein named Stimulator of Interferon Genes (STING), which induces an inflammatory immune reaction. From time to time, the material

    Analysts recognize interface among ALS and collection of DNA-RNA hybrids in the genome

    Researchers from the University of Seville and the University of Pavia have identified a connection between Amyotrophic Lateral Sclerosis (ALS) and the accumulation of DNA-RNA hybrids in the genome. The accumulation of these hybrids causes increased genomic damage and boosts genetic instability. This finding will make it possible to better understand the molecular basis of

    New examination reveals insight into complex brain measure that learns and structure new memories

    Making memories involves over seeing friends or taking photos. How neurons do so –reaching out arm-like dendrites to communicate with other neurons–requires a ballet of genes, signaling molecules, cellular scaffolding and protein-building machinery. A new study from scientists at Scripps Research and the Max Planck Florida Institute for Neuroscience finds a fundamental role for one

    Researchers examine how oxygen radicals secure against cancer

    Initially, oxygen radicals – reactive oxygen species, or ROS for short – were thought of as exclusively harmful in the body. They’re produced, by way of example, by smoking or UV radiation. Because of their high reactivity, they could damage many important molecules in cells, including the hereditary molecule DNA. As a result, there’s a

    Study uncovers the complex cell mechanism of Ebola

    Mount Sinai researchers discovered the intricate cellular mechanisms of Ebola virus. This could help to explain the severe effects on people and provide potential treatment or prevention. The team published a study in mBio that showed how VP24, a protein from the Ebola virus interacts with the double-layered cell membrane (known as the nucleus) and