Blend of nanotechnology and hereditary designing for managing lethal malignant growth stemness Kumar Jeetendra | August 17, 2020 The development of chemotherapeutic agents with discerning anti-cancer actions is unattractive due to the emergence of resistance, inadequate targeting of cancer tissues, and subsequent metastasis. One of tumor attribute cellular types, cancer stem cells have become associated with cancer development and metastasis, representing self-renewal and their propensity to join the flow. Scientists at Japan Advanced …
Amniotic liquid undifferentiated cells may prompt better treatment for ischemic stroke Kumar Jeetendra | October 7, 2020 A study published today in STEM CELLS Translational Medicine points the way to a potential new avenue of treatment for ischemic stroke. The study, led by Annamaria Cimini, Ph.D., of the University of L’Aquila, and Liborio Stuppia, M.D., of D’Annunzio University, Italy, shows how the secretome of amniotic fluid stem cells can restore neuronal plasticity …
Researchers use quality treatment to recover harmed optic nerve filaments Kumar Jeetendra | November 5, 2020 Scientists have used gene therapy to regenerate damaged nerve fibers from the eye, in a discovery that could aid the development of new treatments for glaucoma, one of the main causes of blindness worldwide. Axons – nerve pathways – in the adult central nervous system (CNS) do not normally regenerate after injury and disease, meaning …
Substances in tick spit actuate insusceptible reaction smothering proteins in cattles Kumar Jeetendra | January 28, 2021 Scientists from Hokkaido University, Japan and Universidade Federal do Rio Grande do Sul and Universidade Federal do Rio de Janeiro, Brazil, have revealed that substances in tick saliva trigger immune response-suppressing proteins in cows that facilitates the transmission of tick-borne diseases. The finding was published in the journal Scientific Reports and could assist in the …
New gold-nanoparticle probes for target recognizable proof of bioactive small molecules Kumar Jeetendra | February 2, 2021 The development of pharmaceutical treatments is difficult — clinicians and researchers know a certain drug can regulate particular functions, but they may not understand how it actually works. Bioactive small molecules are chemical compounds, such as pharmaceuticals, that can be readily delivered to and interact with a human body’s cells. By binding to specific proteins, …
Intense openness of lung tissue to vape airborne lesserly affects gene expressionthan cigarette smoke Kumar Jeetendra | March 21, 2021 A new peer-reviewed study published in the journal Toxicological Research & Application reveals acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression in contrast to smoke from combustible cigarettes. The study included sub-cytotoxic vulnerability to cells in a 3D human bronchial model (MucilAirTM) to nicotine-containing vape …
Study maps design and system of a membrane enzyme that assumes part in inflammation, cancer Kumar Jeetendra | March 21, 2021 Most drugs operate via the membranes that surround the body’s cells. The analysis, which is printed in the journal Nature Communications, can make a significant contribution to the development of potential drugs. The cells’ equal to organs, the organelles, are enclosed by membranes. Embedded in the cell’s external and internal membranes are proteins that regulate …
New expected objective for treating metastasized oral malignant melanoma in dogs Kumar Jeetendra | April 23, 2021 Scientists have shown that the biological molecule PD-L1 is a possible target for the treatment of metastasized oral malignant melanoma in dogs. There are a number of cancers that affect dogs, but there are far fewer diagnosis and treatment options for these canine cancers. However, because dogs and humans are both mammals, it is very …
Researchers examine how oxygen radicals secure against cancer Kumar Jeetendra | April 26, 2021 Initially, oxygen radicals – reactive oxygen species, or ROS for short – were thought of as exclusively harmful in the body. They’re produced, by way of example, by smoking or UV radiation. Because of their high reactivity, they could damage many important molecules in cells, including the hereditary molecule DNA. As a result, there’s a …
Researchers examine signal necrotic cells that prompt phagocytic cells to overwhelm the dying cell Kumar Jeetendra | May 8, 2021 As people keep their homes clean and clutter in check, a crew of cells within the body is in charge of clearing the waste that the body generates, including cells that are dying. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means’eating cells’ “Phagocytosis is quite important for the body’s …
Dietary components hold guarantee for working on the health and wellbeing of grown-ups Kumar Jeetendra | January 26, 2022 Research suggests that nutritional supplements that target specific mechanisms that are associated with age-associated cellular decay (AACD), have the potential to improve health and well-being for adults. “Cellular Nutrition and Its Influence on Age-Associated Cellular Decline,” the latest issue of The Gerontological Society of America’s What’s Hot newsletter with accompanying infographic, provides an overview of …