Pancreatic β cell-inferred exosomal miR-29s control glucose homeostasis Kumar Jeetendra | January 24, 2021 In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang’s team at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig’s group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in reaction to high levels of free fatty acids (FFAs). Formerly, Chen-Yu Zhang’s team identified …
New gold-nanoparticle probes for target recognizable proof of bioactive small molecules Kumar Jeetendra | February 2, 2021 The development of pharmaceutical treatments is difficult — clinicians and researchers know a certain drug can regulate particular functions, but they may not understand how it actually works. Bioactive small molecules are chemical compounds, such as pharmaceuticals, that can be readily delivered to and interact with a human body’s cells. By binding to specific proteins, …
Gene panel test empowers exceptionally exact diagnosis of liposarcomas Kumar Jeetendra | February 5, 2021 Scientists have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel evaluation which allows for highly accurate diagnosis of the most frequent kinds of liposarcoma. The new assay is described in The Journal of Molecular Diagnosis, published by Elsevier. Liposarcomas are a type of malignant cancer that is …
Hereditary components of human gut microbiota are key to wellbeing Kumar Jeetendra | February 6, 2021 Neanderthals’ gut microbiota already contained some beneficial micro-organisms that are also found within our own intestine. An international research group headed by the University of Bologna achieved this result by extracting and analyzing ancient DNA from 50,000-year-old fecal sediments sampled at the archaeological site of El Salt, near Alicante (Spain). Published in Communication Biology, their …
An upgraded interaction to detach and cleanse magnetic nanoparticles Kumar Jeetendra | February 20, 2021 Magnetic nanoparticles biosynthesized by germs might soon play an significant role in biomedicine and biotechnology. Researchers at the University of Bayreuth have developed and optimized a procedure for the purification and isolation of the particles from bacterial cells. In initial tests, magnetosomes showed good biocompatibility when compared with human cell lines. The results presented in …
Study uncovers immune defense system that shields the lungs from viral diseases Kumar Jeetendra | March 18, 2021 Scientists have discovered a previously unknown arm of the immune defense system that protects the lung from lethal viral infections. Respiratory diseases caused by viruses such as influenza A and SARS-CoV-2 cause harm not only through their own activities, but also from collateral damage as the immune system reacts to combat the infection. A timely …
A solitary archaeal compound can create a spectacular scope of regular and non-common cardiolipins Kumar Jeetendra | May 7, 2021 Cells of all life forms are surrounded by a membrane that’s made of phospholipids. One of them are the cardiolipins, which form another class due to their distinctive structure. When studying the enzyme that’s responsible for generating cardiolipins in archaea (single-cell organisms that constitute a separate domain of life), biochemists at the University of Groningen …
Scientists distinguish new compound that may forestall heart arrhythmia risk from basic drugs Kumar Jeetendra | May 16, 2021 Dozens of commonly used drugs, including antibiotics, antinausea and anticancer medications, have a potential side effect of lengthening the electrical event that causes regeneration, creating an irregular heartbeat, or cardiac arrhythmia called acquired Long QT syndrome. While safe in their current dosages, some of these drugs might have a more therapeutic benefit at higher doses, …
New testing protocols for SARS-CoV-2 can handle a huge number of tests inside 48 hours Kumar Jeetendra | May 25, 2021 Researchers in the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is printed in the journal Nature Communications and might be adapted to many more pathogens. The COVID-19 pandemic has lasted more than a year and continues to …
New system joins PC programming and cryo-EM to decide 3D constructions of RNA-only molecules Kumar Jeetendra | August 16, 2021 The single-stranded gene material RNA, also known as RNA, is most well-known for its ability to guide the assembly of proteins and carry the genetic code for viruses such as HIV and SARS-CoV-2. Scientists discovered a hidden talent 40 years ago: It can catalyze chemical reaction in cells, including joining and snipping RNA strands. This …
New technique to make a modest and rapid COVID-19 test dependent on isothermal amplification Kumar Jeetendra | December 30, 2021 Russian researchers have devised the method to make an affordable and quick COVID-19 test that relies on isothermal amplifying. According to their paper in Applied Biochemistry and Microbiology The using this method can allow researchers to create universal test methods for any COVID-19 variations. There are many options for devices that detect the presence of SARS-CoV-2 within human …
OmniBRx Biotechnologies and Translational Health Science and Technology Institute (THSTI) Announce Collaboration for Innovations in Cell Therapy Kumar Jeetendra | August 22, 2024 OmniBRx Biotechnologies Pvt Ltd, a pioneer in bioprocess engineering, is thrilled to announce its strategic collaboration with the Translational Health Science and Technology Institute (THSTI), an institute of Biotechnology Research and Innovation Council (BRIC), Department of Biotechnology, Ministry of Science and Technology, Govt of India. The aim of this alliance is to drive the implementation …
