Chemists propose another domino response to deliver organic compound against cancers Kumar Jeetendra | October 12, 2020 A group of chemists in RUDN University suggested a new response to produce organic compounds in 1 vessel. The end products proven to be effective against the cells of carcinomas, including drug-resistant ones. The new reaction was explained from the Bioorganic Chemistry journal. For many organic substances synthesis is a multistage process of step-by-step molecule …
Biocompatible photooxygenation catalyst could be conceivably used to treat amyloid infections Kumar Jeetendra | November 26, 2020 The catalyst was able to oxygenate Aβ embedded beneath the skin of a living mouse, and diminished intact Aβ degree in AD-model mouse brain. The new catalyst is potentially useful for the treatment of peripheral amyloid diseases and AD. Toxic aggregation of amyloid peptide and protein is closely associated with a number of human diseases. …
Trinity crew uncovers mutations connected with early onset dementia Kumar Jeetendra | December 22, 2020 Researchers at Trinity College Dublin today announced a significant advance in our knowledge of an early onset form of dementia which may also advance our understanding of conditions such as Alzheimer’s disease. Adult onset Leukoencephalopathy with axonal Spheroids and Pigmented glia (ALSP) is an ultra-rare condition characterized by mutations in a gene named Colony stimulating …
UH scientist attempting to recognize likely new therapeutic target for kidney sickness Kumar Jeetendra | January 14, 2021 In the past year, high serum suPAR levels also have been found to predict kidney and multiple organ failure in hospitalized patients with COVID-19. “FSGS is a particularly insidious kidney disease. In many patients, it inexorably leads to kidney failure and we don’t have much to offer to stop it, and worse still, in most …
Novel device can add or eliminate sugar from proteins Kumar Jeetendra | March 12, 2021 Sugar has been called “evil,” “toxic,” and “poison.” But the body needs sugars, also. Sugar molecules help cells recognize and fight germs and viruses, shuttle proteins from cell to cell, and make sure those proteins function. Too much or too small can give rise to a range of maladies, including neurodegenerative diseases like Alzheimer’s, diabetes, …
Imbalanced bacterial community in the gums connected to Alzheimer’s infection biomarker Kumar Jeetendra | April 12, 2021 Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta–a key biomarker for Alzheimer’s disease–in their cerebrospinal fluid (CSF), according to new research from NYU College of Dentistry and Weill Cornell Medicine. However, this imbalance in oral bacteria was not associated with another Alzheimer’s biomarker …
Scientists find how Rift Valley fever virus enters cells Kumar Jeetendra | September 24, 2021 Rift Valley fever virus causes economically tragic hemorrhagic outbreaks in livestock, including cattle, goats, and sheep. The mosquito-borne infections can lead to the spread of infection to people who work with animals that are dying or dead often causing many human infections as well as many deaths. Rift Valley fever, for which there isn’t a …
